Results 51 to 60 of about 49,600 (261)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Multidimensional diffusion processes in dynamic online networks.

PLoS ONE, 2020
We develop a dynamic matched sample estimation algorithm to distinguish peer influence and homophily effects on item adoption decisions in dynamic networks, with numerous items diffusing simultaneously.
David Easley, Eleonora Patacchini, Christopher Rojas   +2 more
doaj   +1 more source

SDE based Generalized Innovation Diffusion Modeling [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2019
Diffusion models are rigorously implemented in marketing research to predict the actual trend of innovations over time. These models can be classified in terms of deterministic and stochastic behavior.
Shakshi Singhal, Adarsh Anand, Ompal Singh   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Trust networks and innovation dynamics of small farmers in Colombia: An approach from territorial system of agricultural innovation

Revista de la Facultad de Ciencias Agrarias, 2020
This study addresses the concepts of territorial systems of agricultural innovation and social network analysis. The general purpose of this research was analyzing a relationship between trust networks (technical, strategic and normative) and the ...
Carlos Julián Ramírez-Gómez, Jorge Robledo Velasquez, Jorge Aguilar-Avila   +2 more
doaj  

Determinants and Configurations of Open Scientific Data Policy Diffusion in China [PDF]

Nongye tushu qingbao xuebao
[Purpose/Significance] Open scientific data policies play a pivotal role in promoting the open sharing, unrestricted access to, and reuse of scientific data, thereby enhancing research efficiency and driving innovation.
CHI Yuzhuo, ZHANG Bing
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

The Impact of Technological Innovativeness on the Intention to Utilize Digital Transformation: An Application of Diffusion of Innovation in the Egyptian Private Universities [PDF]

المجلة العربية للإدارة
The purpose of this research is to empirically examine the impact of diffusion of innovation (DOI) on adoption intention to utilize digital transformation, as well as to examine the moderation role of gender and education level between diffusion of ...
Dalia Samy Abdelazeem Soliman, Rasha Abd El Aziz Youssef Shalaby, Nevien Farouk Khourshed, Dalia Fahmy Amara   +3 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source