Results 81 to 90 of about 72,700 (276)

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Technology, Intergovernmental Pressure, and the Diffusion of Online Budget Disclosure in China: A TOE and Policy Diffusion Perspective

Systems
Despite nationwide transparency mandates and expanding digital infrastructure, Chinese local governments adopted online budget disclosure at markedly different times. This study explains this staggered diffusion by integrating the Technology–Organization–
Yike Li, Jiao Wang, Xinran Xu
doaj   +1 more source

The Adoption and Diffusion of eLearning in UK Universities: A Comparative Case Study Using Giddens’s Theory of Structuration [PDF]

, 2011
This exploratory study identifies the factors that influence the adoption and diffusion of instructional technology at five prominent universities in the United Kingdom. The study examines the organisational factors that enable and inhibit organisational
Gurmak Singh, Glenn Hardaker, Hardaker, Glenn, Singh, Gurmak   +3 more
core   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

DIFUSI KEBIJAKAN PENGARUSUTAMAAN GENDER PADA INDIVIDU: REFLEKSI TERHADAP METODE PENELITIAN DIFUSI

Jurnal Penelitian dan Evaluasi Pendidikan, 2013
Penelitian ini bertujuan untuk menemukan model kon-septual difusi kebijakan, faktor-faktor penentu adopsi, dan metode penelitian difusi pengarusutamaan gender (PUG).
Mami Hajaroh
doaj  

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Revealing drivers of green technology adoption through explainable Artificial Intelligence

Advances in Applied Energy
Effective governance of energy system transformation away from fossil resources requires a quantitative understanding of the diffusion of green technologies and its key influencing factors. In this article, we propose a novel machine learning approach to
Dorothea Kistinger, Maurizio Titz, Philipp C. Böttcher, Michael T. Schaub, Sandra Venghaus, Dirk Witthaut   +5 more
doaj   +1 more source

The diffusion of new technology: adoption subsidies, spillovers, and transaction costs. [PDF]

We establish the relation between optimal subsidy rates and spillovers from the sequential adoption of a new technology, we find that they evolve in the same direction over time. We show that spillovers, hence the subsidy rates, need not be monotonic. We
Chokri Dridi, Naceur Khraief
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Intra-Firm Adoption Decisions [PDF]

The subject of this paper is intra-firm adoption decisions, a relatively unexplored research area in the marketing literature. In particular, we investigate which factors influence the intra-firm adoption decisions regarding the common European currency ...
Wierenga, B., Everdingen, Y.M. van
core