Results 81 to 90 of about 32,710,223 (183)

A cross‐species post‐translational modification profiling of histones by LC‐MS/MS revealed conserved oxidative modifications in plants

New Phytologist, Volume 252, Issue 2, Page 538-545, October 2026.
Conservation of post‐translational modifications (PTMs) in histones across six plant species.
Sau‐Shan Cheng, Wai‐Ching Sin, Yuen‐Yi Chau, Hon‐Ming Lam   +3 more
wiley   +1 more source

Endogenous ADP-ribosylation for eukaryotic elongation factor 2: evidence of two different sites and reactions

, 2006
Eukaryotic elongation factor 2 can undergo ADP-ribosylation in the absence of diphtheria toxin under the action of an endogenous transferase. The investigation which aimed to gain insight into the nature of endogenous ADP-ribosylation revealed that this ...
Ergen, Kivanc, Nurten, Rüstem, Bermek, Engin, Bektas, Muhammet   +3 more
core   +1 more source

Discovery of ARF1-targeting inhibitor demethylzeylasteral as a potential agent against breast cancer

Acta Pharmaceutica Sinica B, 2022
Jie Chang, Ruirui Yang, Lifan Chen, Zisheng Fan, Jingyi Zhou, Hao Guo, Yinghui Zhang, Yadan Liu, Guizhen Zhou, Keke Zhang, Kaixian Chen, Hualiang Jiang, Mingyue Zheng, Sulin Zhang   +13 more
doaj   +1 more source

ARL14 as a Prognostic Biomarker in Non-Small Cell Lung Cancer

Journal of Inflammation Research, 2021
Binbin Zhang,1,* Aiqun Xu,2,* Dong Wu,1,* Wanli Xia,3,* Pulin Li,1 Enze Wang,1 Rui Han,1 Peng Sun,1 Sijing Zhou,4,5 Ran Wang1 1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University,
Zhang B, Xu A, Wu D, Xia W, Li P, Wang E, Han R, Sun P, Zhou S, Wang R   +9 more
doaj  

The unfolded protein response links ER stress to cancer-associated thrombosis

JCI Insight, 2023
Thrombosis is a common complication of advanced cancer, yet the cellular mechanisms linking malignancy to thrombosis are poorly understood. The unfolded protein response (UPR) is an ER stress response associated with advanced cancers.
Oluwatoyosi Muse, Rushad Patell, Christian G. Peters, Moua Yang, Emale El-Darzi, Sol Schulman, Anna Falanga, Marina Marchetti, Laura Russo, Jeffrey I. Zwicker, Robert Flaumenhaft   +10 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, Volume 600, Issue 17, Page 2564-2578, September 2026.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Knockout of SsArl1 Leading to Enhanced Virulence in Sclerotinia sclerotiorum

Journal of Fungi
Sclerotinia sclerotiorum is a formidable soilborne fungus that wreaks havoc on numerous crops globally. While the role of ADP-ribosylation factor-like 1 (Arl1) small GTPases in vesicular trafficking and fungal development is well-documented, their ...
Zuyan Cheng, Kunmei Wang, Jianhua Tong, Jiancheng Cao, Lei Qin, Shitou Xia   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, Volume 600, Issue 17, Page 2547-2563, September 2026.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Activators and Effectors of the Small G Protein Arf1 in Regulation of Golgi Dynamics During the Cell Division Cycle

Frontiers in Cell and Developmental Biology, 2018
When eukaryotic cells divide, they must faithfully segregate not only the genetic material but also their membrane-bound organelles into each daughter cell.
Catherine L. Jackson
doaj   +1 more source