Results 171 to 180 of about 15,419 (219)

PERADIGM: Phenotype embedding similarity-based rare disease gene mapping. [PDF]

open access: yesPLoS Genet
Zheng W   +6 more
europepmc   +1 more source

A novel ADPKD model using kidney organoids derived from disease-specific human iPSCs

Biochemical and Biophysical Research Communications, 2020
Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder which manifests progressive renal cyst formation and leads to end-stage kidney disease.
Keisuke Okita   +2 more
exaly   +2 more sources

Safe Nanocomposite‐Mediated Efficient Delivery of MicroRNA Plasmids for Autosomal Dominant Polycystic Kidney Disease (ADPKD) Therapy

Advanced Healthcare Materials, 2019
There is currently no cure for gene mutation‐caused autosomal dominant polycystic kidney disease (ADPKD). Over half of patients with ADPKD eventually develop kidney failure, requiring dialysis or kidney transplantation.
Si-Tse Jiang, Yi-Che Lee, Yuan-Yow Chiou
exaly   +2 more sources

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