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Autosomal dominant polycystic kidney disease

The Lancet, 2019
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and one of the most common causes of end-stage kidney disease. Multiple clinical manifestations, such as enlarged kidneys filled with growing cysts, hypertension, and multiple extrarenal complications, including liver cysts, intracranial aneurysms, and ...
Emilie, Cornec-Le Gall, Ahsan, Alam, Ronald D, Perrone   +2 more
semanticscholar   +7 more sources

Autosomal Dominant Polycystic Kidney Disease [PDF]

Advances in Chronic Kidney Disease, 2010
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic form of kidney disease and affects 1 in 500 to 1,000 individuals worldwide, regardless of ethnicity. It is characterized by progressive renal cyst formation, which distorts normal kidney architecture and ultimately causes 5% of all cases of end-stage renal disease (ESRD) in
V E, Torres, P C, Harris
semanticscholar   +5 more sources

Autosomal dominant polycystic kidney disease [PDF]

BMJ, 1994
When the BMJ last published an editorial on adult autosomal dominant polycystic kidney disease1 there was no chromosomal assignment for the disorder. Two have since been recognised. The first, designated PKD-1,2 has been localised to a narrow region of about half a million base pairs on the short arm of chromosome 16, but the specific gene has not yet ...
A K, Saggar-Malik, S, Jeffery, M A, Patton   +2 more
openaire   +3 more sources

Autosomal dominant polycystic kidney disease

BMJ, 2016
#### What you need to know Polycystic kidney disease (PKD) is an inherited condition defined by the pathological development of fluid-filled cysts throughout the kidneys leading to organ enlargement (fig 1⇓) and chronic kidney disease. Autosomal dominant polycystic kidney disease (ADPKD) is the commonest inherited kidney disease1 and is the fourth ...
R. Simms
semanticscholar   +5 more sources

Autosomal dominant polycystic kidney disease

Clinical medicine (London), 2018
Based on an estimated population prevalence of between 1 in 400 and 1 in 1000, there are over 60,000 individuals with or at risk of developing complications associated with autosomal dominant polycystic kidney disease (ADPKD) in the United Kingdom. This equates to over 300,000 people in the United States and 7 million worldwide.
Albert C. M. Ong, Richard Sandford
semanticscholar   +3 more sources

Coronary aneurysms and dissections in a patient with autosomal dominant polycystic kidney disease: a case report [PDF]

Journal of Medical Case Reports
Background Autosomal dominant polycystic kidney disease is the most common hereditary kidney disorder, characterized by the progressive formation of renal cysts due to genetic mutations.
Maria Júlia Carnieletto Nicolodi, Gustavo Carnieletto Garcia, Md. José Knopfholz   +2 more
doaj   +2 more sources

Dual Monogenic Cystic Disease Case Report: Autosomal Dominant Polycystic Kidney Disease and Autosomal Dominant Polycystic Liver Disease [PDF]

Clinical Case Reports
Autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD) are inherited cystic conditions with overlapping features but distinct genetic causes and clinical courses.
Anna Katya Brossart, Kathryn Curry, Sumit Punj, Tarek Darwish, Hossein Tabriziani   +4 more
doaj   +2 more sources

Autosomal Dominant Polycystic Kidney Disease: A Review. [PDF]

JAMA
ImportanceAutosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive development of kidney cysts and is the most common inherited kidney disorder worldwide. ADPKD accounts for 5% to 10% of kidney failure in the US and Europe, and its prevalence in the US is 9.3 per 10 000 individuals.ObservationsADPKD is typically diagnosed in
Chebib FT, Hanna C, Harris PC, Torres VE, Dahl NK.   +4 more
europepmc   +3 more sources

Autosomal dominant polycystic kidney disease

Radiopaedia.org, 2013
Stefan Somlo, Vicente E. Torres, Michael J. Caplan   +2 more
semanticscholar   +3 more sources

Immune microenvironment in autosomal dominant polycystic kidney disease [PDF]

Genes and Diseases
Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary renal disorder characterized by the progressive development of fluid-filled cysts within the kidneys, leading to renal dysfunction and potentially life-threatening complications.
Cheng Xue, Xinming Li, Chenchen Zhou, Changlin Mei, Zhiguo Mao   +4 more
doaj   +2 more sources