Influence of combined CYP2C19 and CYP2D6 phenotypes on adverse drug reactions in patients with major depressive disorder: a clinical cohort study. [PDF]
Görnert C +6 more
europepmc +1 more source
The impact of public drop‐off boxes and autonomous delivery robots in last‐mile delivery
Abstract The growing concern over emissions from last‐mile logistics is motivating the development of innovative delivery models aimed at reducing environmental impact and traffic congestion. To this end, we propose a last‐mile delivery scheme based on both public drop‐off boxes and autonomous delivery robots.
Gianpaolo Ghiani +3 more
wiley +1 more source
The Effect of Cannabidiol on Cancer-Pathway Genes in Doxorubicin-Sensitive and Resistant Breast Cancer Cells. [PDF]
Çifçi KU +6 more
europepmc +1 more source
ABSTRACT Two coastal dolphin species, the common bottlenose dolphin (Tursiops truncatus—Tt) and the short‐beaked common dolphin (Delphinus delphis—Dd), co‐occur along the southern Israeli Mediterranean coast, where the critically endangered Dd population faces ecological pressures, potentially including competitive exclusion by that of the Tt ...
Y. E. Zuriel +6 more
wiley +1 more source
Toward Optimized Platinum Therapy: A Risk Prediction Model for Toxicity Based on Platinum Accumulation and Its Impact on Treatment Outcomes. [PDF]
Huang X +6 more
europepmc +1 more source
Strengthening Pharmacovigilance Reporting for Withdrawal Reactions to Support Deprescribing
Pharmacovigilance plays a crucial role in post‐marketing surveillance of medicines and relies on the spontaneous reporting of adverse drug reactions (ADRs). Discontinuation of a drug can cause clinically relevant signs and symptoms, including withdrawal reactions; however, this subset of ADRs is not fully accommodated in current pharmacovigilance ...
Zakir Khan, Frank Moriarty
wiley +1 more source
Prevalence, Patterns, and Factors Associated With Adverse Drug Reactions Among People Living With HIV Receiving Antiretroviral Therapy at a Secondary Healthcare Facility in Ghana: A Retrospective Cross-Sectional Study. [PDF]
Ampaabeng-Kyeremeh A +9 more
europepmc +1 more source
Dual‐drug‐loaded liposomes enable the simultaneous delivery of hydrophilic and hydrophobic therapeutics to tumors, enhancing anticancer efficacy and overcoming multidrug resistance. Through rational formulation design and surface functionalization, these systems improve tumor targeting, modulate efflux mechanisms and EMT, and achieve synergistic ...
Neelam Sinha +4 more
wiley +1 more source
Mediation as Therapeutic Resolution for Conflicts about Patient Health and Care
This article shows how mediation can be a form of ‘therapeutic resolution’ in adult health and care disputes. These are typically disputes that arise under the Mental Capacity Act 2005 about an adult's best interests but also include complaints about adult health and care provision.
Jaime Lindsey
wiley +1 more source

