PTRF Confers Melanoma‐Acquired Drug Resistance Through the Upregulation of EGFR
Cell Proliferation, Volume 59, Issue 2, February 2026.The upregulation of PTRF, a critical caveolar component, and the concomitant increase in caveolae number potentiate cellular proliferation and survival pathways, thereby contributing to melanoma drug resistance. ABSTRACT Melanoma is the most serious type of skin cancer. About half of all melanomas have activating BRAF mutations.
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Transcriptional PBR cycles at pericentromeric repeats cause gross chromosomal rearrangements through Rad52-dependent ADR-loop formation. [PDF]
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Comparative study of endocuff assisted colonoscopy and artificial intelligence in colonoscopy in adenoma and polyp detection: a randomized, back-to-back study. [PDF]
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DeepADR: multimodal prediction of adverse drug reaction frequency by integrating early-stage drug discovery information via Kolmogorov-Arnold networks. [PDF]
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The quantity and severity of adverse drug reactions experienced by patients with multi-drug resistant tuberculosis in the Ugu District. [PDF]
BMC Infect DisRamasir S, Oosthuizen F, Bangalee V.
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Hybrid Strategies for CTO PCI: A Systematic Review and Meta-Analysis of Antegrade and Retrograde Techniques. [PDF]
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Research and practice on key drug safety monitoring under the normalization of centralized procurement: A case study of 13 selected drugs in a Province. [PDF]
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Best of United European Gastroenterology Week 2025
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
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