Results 21 to 30 of about 36,582 (247)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A young person’s perspective of administrative data research

International Journal of Population Data Science
Recent public attitudinal studies have shown that the public want to know of the benefits of administrative data research. However, a common challenge is translating this information in an engaging and meaningful way. To bridge this gap, ADR UK hosted a
Rianna Romeo, Shayda Kashef
doaj   +1 more source

Monogràfic "Justícia relacional i mètodes electrònics de resolució (ODR): cap a una harmonització tècnica i legal"

IDP, 2010
La resolució de les controvèrsies al marge de les instàncies judicials o en col·laboració amb elles és un fenomen que ha anat consolidant una rica varietat de pràctiques, mètodes i dinàmiques designats en general amb els acrònims ADR (Alternative ...
Aura Ester Vilalta
doaj   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

Advanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà, Giulia Cazzador, Roberta Fabbri, Matteo Calosi, Alessandro Silvestri, Andrea Candini, Fabiola Liscio, Franco Corticelli, Aikaterini Konstantoulaki, Andrea D'Iorio, Marco Caprini, Vincenzo Palermo, Monica Bertoldo, Valentina Benfenati, Chiara Zanardi, Emanuele Treossi   +15 more
wiley   +1 more source

Health and justice related substance misuse in Wales: creating an e-cohort of intergenerational households

International Journal of Population Data Science
Objectives Household substance misuse (SM) is associated with child deprivation and worse physical and mental health. This study utilised linked healthcare, justice, and social care data in Wales for the first time, to create a reusable cohort of ...
Hywel T Evans, Ian Farr, Grace Bailey, Gareth Davies, Josh Dixon, Sam Fallick, Joanne Maimaris, Columbus Ohaeri, Olabambo Oluwasuji, Ryan Phillips, Matthew Skermer, Delyth James, Josie Smith   +12 more
doaj   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Live research dialogue on the benefits, costs and utility of synthetic data for researchers

International Journal of Population Data Science
Objectives • To explore use cases and characteristics of synthetic data that make it useful for research. • To discuss governance frameworks essential for the routine creation, dissemination, and use of synthetic data.
Emily Oliver, Fiona Lugg-Widger, Maureen Haaker, Cristina Magder, Emma Gordon   +4 more
doaj   +1 more source

Temperature Impact in LoRaWAN—A Case Study in Northern Sweden

Sensors, 2019
LoRaWAN has become popular as an IoT enabler. The low cost, ease of installation and the capacity of fine-tuning the parameters make this network a suitable candidate for the deployment of smart cities.
Níbia Souza Bezerra, Christer Åhlund, Saguna Saguna, Vicente A. de Sousa   +3 more
doaj   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

Advanced Science, EarlyView.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen, Lei Huang, Yingtong Jiang, Guohong Zhao, Mengyuan Zhu, Xiulian Lu, Lang Lang, Akinpelumi Oluwatobiloba Esther, Longhao Fan, Yuqi Jiang, Chang Sun, Xiaoling Zhang, Kun Zhou, Xiaoming Ji, Minjian Chen   +14 more
wiley   +1 more source

Undressing DReSS as p-i mediated disease

Allergology International
Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) is a severe T cell-mediated hypersensitivity reaction. T cells in DReSS are stimulated via the p-i mechanism (pharmacological interaction with immune receptors), where the drug shows an off ...
Werner J. Pichler, Lester Thoo, Daniel Yerly, Tim Peyer, Oliver Hausmann, Yannick Muller, Marianne Lerch, Lukas Joerg, Thomas Harr, Katja Martin   +9 more
doaj   +1 more source