Results 41 to 50 of about 74,769 (254)

Adipose‐derived mesenchymal stem cell injection into the KI10 acupoint mitigates cartilage damage in KOA rats through PGE2‐mediated α7nAChR/NF‐κB pathway

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In our research, KOA rat models were established and treated with ADSC injection into the KI10 acupoint. Pain relief, behavioral function, and joint structural improvements were systematically assessed using ethological tests, imaging, histopathological staining, transmission electron microscopy, and molecular analyses.
Mengwei Dong   +7 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Resolució electrònica de disputes. Primeres reflexions entorn de la necessitat d'un marc normatiu internacional

open access: yesIDP, 2010
Les modalitats electròniques de gestió i resolució de controvèrsies es troben en un moment d'inflexió, a causa de certs obstacles que n'impedeixen, de facto, la perfecta incardinació en el conjunt del sistema judicial.
Aura Esther Vilalta
doaj   +1 more source

How to improve the adenoma detection rate in colorectal cancer screening? Clinical factors and technological advancements

open access: yesArchives of Medical Science, 2019
Introduction Colonoscopy has been widely regarded as the gold standard in colorectal cancer (CRC) screening. Within recent years different endoscopic imaging techniques have been introduced to improve the quality of colonoscopy.
Maciej Matyja   +5 more
doaj   +1 more source

Public attitudes to population data research in 2022.

open access: yesInternational Journal of Population Data Science, 2022
Objectives Broad public acceptability of research using data and statistics entails demonstrating trustworthiness and understanding public needs to maximise public benefit.
Shayda Kashef   +2 more
doaj   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Guiding principles for the provision of synthetic data

open access: yesInternational Journal of Population Data Science
Synthetic data is an emerging tool for those learning to use and/or planning to use secure datasets, and for collaborators on secure data projects. However, there is a lack of consistency in its provision, and this affects both trust in its use and ...
Emily Oliver
doaj   +1 more source

Dispute Resolution in Modern Treaties: Evolutions, Observations and Next Steps

open access: yesArctic Review on Law and Politics, 2020
In Canada, comprehensive land claims agreements – often called modern treaties – between the government and Indigenous nations include provisions prescribing how disputes between treaty parties are to be resolved.
David Wright
doaj   +1 more source

Global Perspectives on ADR: Indonesia [PDF]

open access: yes, 2004
This chapter contains articles on the development of Alternative Dispute Resolution (ADR) in Indonesia started with the enactment of Act No. 30 of 1999 on Arbitration and Alternative Dispute Resolution (the Arbitration Act).
Simandjuntak, Marcella Elwina   +2 more
core   +1 more source

Stock-ADR Arbitrage: Microstructure Risk [PDF]

open access: yes, 2019
This paper is the first to highlight that the stock-ADR arbitrage pair trading found by Alsayed and McGroarty (2012) is directly influenced by the market microstructure of ADRs.
Mitra, S.   +7 more
core   +1 more source

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