Results 281 to 290 of about 783,304 (397)

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 8, Page 1004-1025, August 2025.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes   +6 more
wiley   +1 more source

Resistance and Aerobic Preconditioning Delays Unloading‐Induced Multisystemic Physiological Changes: The NEBULA Project

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
This graphical abstract illustrates the NEBULA project, which examines combined high intensity preconditioning exercise as a countermeasure to microgravity. Mice underwent 3 weeks of training before 7–21 days of hindlimb unloading. After 7 days of simulated microgravity, trained mice showed positive adaptations related to the prevention of ...
Théo Fovet   +18 more
wiley   +1 more source

Mammalian Tolerance to Amino Acid Heterochirality

open access: yesChemBioChem, Volume 26, Issue 13, July 11, 2025.
Organisms preferentially use l‐amino acids (l‐AAs). However, de novo synthesized l‐AAs are in part converted to d‐AAs. The ribosome has a robust system to use l‐AAs for protein synthesis, whereas non‐ribosomal synthesis can also use d‐AAs. Furthermore, some AA residues can be post‐translationally isomerized through enzymatic or spontaneous processes ...
Sakiko Taniguchi   +4 more
wiley   +1 more source

THE ADRENAL CORTEX [PDF]

open access: yesJournal of Clinical Pathology, 1963
openaire   +2 more sources

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