Results 101 to 110 of about 37,949 (281)

Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension

Scientific Reports
Hypertension remains a leading cause of cardiovascular and kidney diseases. Failure to control blood pressure with ≥ 3 medications or control requiring ≥ 4 medications is classified as resistant hypertension (rHTN) and new therapies are needed to reduce ...
Shan-Shan Zhang, Lance Larrabee, Andrew H. Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C. Hartman, Abby Whitnall, Joseph Mason, Nicholas P. Barton, Audrey Y. Chu, Jonathan M. Davitte, Adam J. Csakai, Caitlin Vestal Tibbetts, Audrey E. Tolbert, Heather O’Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P. Mayer, Patrick Koenig, Davide Foletti, Steven J. Pitts, Christine G. Schnackenberg   +29 more
doaj   +1 more source

A Case of Renal Metastasis of Urothelial Carcinoma With Trophoblastic Differentiation Successfully Treated With Robot‐Assisted Partial Nephrectomy

IJU Case Reports, EarlyView.
ABSTRACT Introduction There are no previous reports of solitary renal metastases from urothelial carcinoma with trophoblastic differentiation, a rare bladder cancer subtype that is pathologically hCGβ positive. Case Presentation A 77‐year‐old male with urothelial carcinoma with trophoblastic differentiation underwent robot‐assisted radical cystectomy ...
Seiichiro Honda, Koichi Uemura, Hiroki Ito, Erika Muraoka, Tomoyuki Tatenuma, Yusuke Ito, Kentaro Muraoka, Hisashi Hasumi, Naomi Kawano, Shoji Yamanaka, Kazuhide Makiyama   +10 more
wiley   +1 more source

Analysis of the Adrenal Gland Is Useful for Evaluating Pathology of the Peripheral Autonomic Nervous System in Lewy Body Disease [PDF]

, 2007
Yuichi Fumimura, Masako Ikemura, Yuko Saito, Renpei Sengoku, Kazutomi Kanemaru, Motoji Sawabe, Tomio Arai, Genta Ito, Takeshi Iwatsubo, Masashi Fukayama, Hidehiro Mizusawa, Shigeo Murayama   +11 more
openalex   +1 more source

Mitotane Treatment for Malignant Leydig Cell Tumor: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction Leydig cell tumors (LCTs), constituting 1%–3% of testicular tumors, are mostly benign, but malignant cases present treatment challenges. We report a malignant LCT case with a notable response to mitotane. Case Presentation A 43‐year‐old male presented with a right testicular induration and was diagnosed with a Leydig cell tumor ...
Daiki Katsura, Mototsugu Muramaki, Takashi Okamoto, Masaya Yamamoto, Mizuki Yutaka, Shohei Morita, Takuya Fujimoto, Yuji Yamada   +7 more
wiley   +1 more source

The Effect of Maternal Behçet's Disease on Fetal Adrenal Gland Sizes

, 2023
Derya Uyan Hendem, Dilek Şahın
openalex   +2 more sources

An unusual presentation of pheochromocytoma accompanied by catecholamine‐induced cardiomyopathy

ESC Heart Failure, EarlyView.
Hugh O.J. Roberts, Alexandru Munteanu, Jonas E. Mertens   +2 more
wiley   +1 more source

Extrachromosomal Circular DNA: Emerging Insights Into Cardiovascular Disease Mechanisms and Biomarker Potential

iLABMED, EarlyView.
Extrachromosomal circular DNA (eccDNA) has quite recently turned out to be a cardinal component in cardiovascular diseases (CVD), governing the gene expression and mechanisms of disease causation. Studies indicated an upregulation of eccDNA in pulmonary arterial hypertension (PAH), which makes it strikingly potential as a sensitive and specific ...
Saim Mahmood Khan, Jawairya Muhammad Hussain, Surraiya Riaz Mahmood Khan, Bushra Nadeem, Tahniyat Naseem, Hammad Jawed, Aina Lashari   +6 more
wiley   +1 more source

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

iMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma, Hangyuan He, Kunpeng Wang, Juanjuan Guo, Liang Liu, Yuting Chen, Bin Li, Hao Xiao, Xufeng Li, Xiaoqian Lu, Tingting Wang, Yinxian Wen, Hui Wang, Liaobin Chen   +13 more
wiley   +1 more source

Gut microbial‐derived 3,4‐dihydroxyphenylacetic acid ameliorates reproductive phenotype of polycystic ovary syndrome

iMeta, EarlyView.
By integrating multi‐level and multi‐omics analyses, we identify 3,4‐dihydroxyphenylacetic acid (DHPAA), a gut microbiota‐derived degradation product of dietary flavonoids, as a key bioactive end‐product responsible for the beneficial effects against polycystic ovary syndrome (PCOS).
Pan Li, Li Xie, Huimin Zheng, Yinglin Feng, Feihong Mai, Wenli Tang, Jiajia Wang, Zixin Lan, Shuaijun Lv, Thisun Jayawardana, Sabrina Koentgen, Shuangbin Xu, Zhengwei Wan, Yunjie Chen, Haiyan Xu, Sj Shen, Fan Zhang, Yuanhao Yang, Georgina Hold, Fangjie He, Emad M. El‐Omar, Guangchuang Yu, Xia Chen   +22 more
wiley   +1 more source

Tratamento cirúrgico da hipertensão arterial secundária com origem na glândula supra-renal

Revista do Colégio Brasileiro de Cirurgiões
Among the main etiologies of secondary arterial hypertension figure out the tumorous affections of adrenal gland, located on cortex - primary aldosteronism (Conn’s syndrome) and Cushing’s syndrome - or at glandular medulla - pheocromocytoma.
Ruy Garcia Marques, Antonio Felipe Sanjuliani   +1 more
doaj   +1 more source