Results 141 to 150 of about 2,389,380 (305)

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

open access: yesSensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa   +5 more
wiley   +1 more source

The Role of Repetitive Transcranial Magnetic Stimulation in Modulating Autonomic Dysfunction in Irritable Bowel Syndrome rTMS for IBS Autonomic Dysfunction

open access: yesSensory Neuroscience, EarlyView.
Irritable bowel syndrome (IBS) is associated with dysregulation of the autonomic nervous system and altered brain–gut communication. rTMS may alleviate IBS symptoms by modulating central autonomic and pain‐processing networks, potentially restoring sympathovagal balance and reducing visceral hypersensitivity.
Aliasghar Karimi   +4 more
wiley   +1 more source

The association between red blood cell distribution width‐to‐albumin ratio and risk of insomnia: A cross‐sectional analysis of National Health and Nutrition Examination Survey and Chinese clinical data

open access: yesSleep Research, EarlyView.
Abstract Background The red blood cell distribution width‐to‐albumin ratio (RAR) is a novel composite biomarker of inflammation and nutritional status, yet its association with insomnia and underlying mechanisms remain poorly understood. Objective To investigate the association between the RAR and insomnia in two independent cohorts, comprising a ...
Jingying Ma   +7 more
wiley   +1 more source

Adrenal gland disorders

open access: yes, 2013
Adrenal gland ...
Patricia Dunning (13098297)
core  

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Identification and Discrimination of Sulfated and Unsulfated Gut‐Hormone Biomarkers in Human Serum by Nanopore

open access: yesSmall, EarlyView.
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Luca Iesu   +3 more
wiley   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida   +7 more
wiley   +1 more source

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