Results 141 to 150 of about 176,228 (323)

Autocrine and paracrine regulation of pituitary endocrine cells

Frontiers in Endocrinology
The anterior pituitary gland is an important endocrine organ composed of a variety of key endocrine cells that regulate the functions of peripheral targeted organs, such as growth, development, behavior, lactation, reproduction and the stability of the ...
Jianmei Yang, Lingyu Li, Lingyu Li, Xiangbo Xie, Xiangbo Xie, Changying Zhao, Chen Chen   +6 more
doaj   +1 more source

Attention‐Deficit/Hyperactivity Disorder Through a Circadian Lens: When the Brain's Clock Disrupts Attention Regulation

Medicine Bulletin, EarlyView.
ABSTRACT Attention‐deficit/hyperactivity disorder (ADHD) is increasingly linked to disturbances in circadian regulation, yet this temporal dimension remains insufficiently integrated into research and clinical practice. This perspective synthesises current evidence on circadian misalignment in ADHD, reframing commonly reported sleep disturbances and ...
Ping Wang, Bo Zeng, Bivek Singh
wiley   +1 more source

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease

Neuroprotection, EarlyView.
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji, Liujia Lu, Kaidong Chen, Ruixuan Zhang, Yao Lu, Yachen Shi, Xiangming Fang   +6 more
wiley   +1 more source

Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension

Scientific Reports
Hypertension remains a leading cause of cardiovascular and kidney diseases. Failure to control blood pressure with ≥ 3 medications or control requiring ≥ 4 medications is classified as resistant hypertension (rHTN) and new therapies are needed to reduce ...
Shan-Shan Zhang, Lance Larrabee, Andrew H. Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C. Hartman, Abby Whitnall, Joseph Mason, Nicholas P. Barton, Audrey Y. Chu, Jonathan M. Davitte, Adam J. Csakai, Caitlin Vestal Tibbetts, Audrey E. Tolbert, Heather O’Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P. Mayer, Patrick Koenig, Davide Foletti, Steven J. Pitts, Christine G. Schnackenberg   +29 more
doaj   +1 more source

Stereotactic body radiation therapy (SBRT) of adrenal gland metastases in oligometastatic and oligoprogressive disease

, 2021
Leonid B. Reshko, Jeremy Gaskins, Craig L. Silverman, Neal Dunlap   +3 more
openalex   +2 more sources

Adrenal Gland Dysfunction and Its Link to Endocrine Disorders: Disfungsi Kelenjar Adrenal dan Kaitannya dengan Gangguan Endokrin

General Background: The adrenal glands, also known as suprarenal glands, are vital endocrine organs located above each kidney. Specific Background: Comprising the cortex and medulla, these glands produce a variety of hormones essential for metabolic ...
Hamza, Duaa Hamad
core  

Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective While RNAseq has enhanced variant interpretation in postnatal cases, its potential in the prenatal setting remains underexplored. This study investigates the utility of RNAseq in prenatal diagnostics by analyzing the expression profiles of cultured chorionic villus samples (cCVS) and amniotic fluid (cAF) samples. Methods We performed
Maria C. Vladoiu, Sen Zhao, Roni Zemet, Christian M. Parobek, Jefferson Cruz Sinson, Stacy Tankersley, Ignatia B. Van den Veyver, Pengfei Liu   +7 more
wiley   +1 more source

Computed tomography, angiographic and scintigraphic semiotics of diseases of the kidneys and adrenal glands

, 2022
I. I. Kamalov, V. V. Korobov, Sergey Rumyantsev, А. A. Akhunzyanov, L. I. Kamalova   +4 more
openalex   +2 more sources

2. Lecture (08.07.2020): Hormones of the adrenal cortex

, 2020
Content: Adrenal glands-anatomy and function; Hypothalamus-pituitary-adrenal (HPA) axis; Hormones of the adrenal glands and effects on target tissues; Diseases or dysregulation of HPA axis and adrenal ...
Iyer-Bierhoff, Aishwarya Murali
core  

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source