Results 181 to 190 of about 2,389,380 (305)

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Development of a Preoperative Difficulty Score for Retroperitoneal Laparoscopic Adrenalectomy: A Single-Center Retrospective Study. [PDF]

J Clin Med
Chen J, Zhang C, Zhang L, Du H, Zhan C.
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

CT-derived abdominal organ volumetrics for predicting recurrence-free and disease-free survival in resected non-small cell lung cancer: a multicenter retrospective cohort study. [PDF]

Transl Lung Cancer Res
Huang H, Gong B, Lou J, Zhu D, Guo Y, Xiang G, Peng S, Li W, Li H, Yang L.   +9 more
europepmc   +1 more source

M1135: Right adrenal gland

Clinical history : The patient is a 37 year old female with longstanding Cushing syndrome.Two attempts at removing micro-adenoma in the pituitary gland in 1977 and 1981 was made.Computer tomography showed a tumour in the right adrenal gland and ...

core  

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Metastatic organ distribution characteristics and prognosis in patients with non-small cell lung cancer. [PDF]

Front Med (Lausanne)
Zhu J, Pan W, Wang Y.
europepmc   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

Early detection of invasive lung cancer and multiorgan metastasis by a collagen-targeted protein MRI contrast agent. [PDF]

Sci Adv
Li D, Bamishaye O, Li S, Qiao J, Akinlotan F, Dorabadizare F, Chen X, Fan Y, Yuan Y, Gui Z, Hekmatyar K, Tóth É, Pallier A, Xu Y, Zhang Y, Ke X, Farris AB, Yang H, Wang JX, Carlisle J, Ramalingam SS, Kirberger M, Grossniklaus H, Yang X, Liu Z, Zhou W, Yang JJ.   +26 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source