Results 51 to 60 of about 243,182 (378)

Adrenalectomy for metastatic disease to the adrenal glands

Journal of British Surgery, 1996
Abstract A policy of supportive treatment is frequently adopted for patients with metastatic disease to the adrenal glands. This study reports an experience with adrenalectomy for adrenal metastasis. Between 1983 and 1993, adrenalectomy was performed in 52 patients for metastasis to the adrenal glands.
C Y, Lo, J A, van Heerden, J A, Soreide, C S, Grant, G B, Thompson, R V, Lloyd, W S, Harmsen   +6 more
openaire   +2 more sources

Computational Analysis of a GST‐Based Long‐Wave Infrared Microring Resonator on a ZnSe Platform as a Photonic Sensor

Advanced Photonics Research, EarlyView.
A Ge2Sb2Te5 (GST)‐based microring resonator is designed and simulated on a ZnSe‐platform that operates in the long‐wave infrared (LWIR) wavelength of 8 μm. The structure demonstrates strong power confinement and high Q‐factor. GST resonator is used for gas and biosensing applications.
Tanzina Rahman, Md. Islahur Rahman Ebon, Amrita Kumar Sana, Jaker Hossain   +3 more
wiley   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

Single‐nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands

Clinical and Translational Medicine
The human adrenal gland is a complex endocrine tissue. Studies on adrenal renewal have been limited to animal models or human foetuses. Enhancing our understanding of adult human adrenal homeostasis is crucial for gaining insights into the pathogenesis ...
Barbara Altieri, A. Kerim Secener, Somesh Sai, Cornelius Fischer, Silviu Sbiera, Panagiota Arampatzi, Stefan Kircher, Sabine Herterich, Laura‐Sophie Landwehr, Sarah N. Vitcetz, Caroline Braeuning, Martin Fassnacht, Cristina L. Ronchi, Sascha Sauer   +13 more
doaj   +1 more source

ADRENALECTOMÍA TRANSPERITONEAL LAPAROSCÓPICA: EXPERIENCIA [PDF]

, 2006
Arch Esp Urol. 2006 Nov;59(9):893-7. [Transperitoneal laparoscopic adrenalectomy: initial experience] [Article in Spanish] Palacios A, Lima E, Massó P, Versos R, Autorino R, Ramos M, Soares J, Marcelo F.
AUTORINO, R., LIMA, E., MARCELO, F., MASSO, P., PALACIOS, A., RAMOS, M., SOARES, J., VERSOS, R.   +7 more
core  

Hypoadrenocorticism in an aged cat [PDF]

, 2018
A 13-year-old, female, neutered, domestic longhair cat was referred to the hospital with a two-month history of fluctuating weakness, lethargy, inappetence and intermittently soft stools.
Fowlie, Samuel J., McKenzie, Jennifer, Ramsey, Ian   +2 more
core   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Adrenal hematopoiesis in a pediatric patient with spherocytosis: A case report and literature review

Radiology Case Reports
Extramedullary hematopoiesis (EMH) is extremely rare in the adrenal glands, especially in children. Because this is an underrecognized condition, the vast majority of cases are diagnosed only after adrenalectomy.
Rawa Bapir, Ismaeel Aghaways, Sharaza Qadir Omer, Rezheen J. Rashid, Shaho F. Ahmed, Hadeel Adnan Yasseen, Hardi M. Dhahir, Honar O. Kareem, Dilan S. Hiwa, Berun A. Abdalla, Fahmi H. Kakamad   +10 more
doaj   +1 more source

Label-free enrichment of adrenal cortical progenitor cells using inertial microfluidics. [PDF]

, 2012
Passive and label-free isolation of viable target cells based on intrinsic biophysical cellular properties would allow for cost savings in applications where molecular biomarkers are known as well as potentially enable the separation of cells with little-
Brinckerhoff, Tatiana Z, Di Carlo, Dino, Dunn, James CY, Hur, Soojung Claire, Walthers, Christopher M   +4 more
core   +2 more sources