Results 61 to 70 of about 241,535 (385)
Sex hormones are molecules produced by the gonads and to a small extent by the adrenal gland, which not only determine the primary and secondary sexual characteristics of an individual, differentiating man from woman, but also participate in the ...
R. Nuzzi, Paolo Caselgrandi
semanticscholar +1 more source
Deprenyl, an old drug with new anticancer potential: Mini review [PDF]
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach+8 more
wiley +1 more source
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka+5 more
wiley +2 more sources
Surgical Management of Metastatic Disease to the Adrenal Gland
Metastatic disease to the adrenal glands can occur in a wide array of malignancies. With the increased use of abdominal imaging, these lesions are diagnosed with more frequency. Diagnostic and laboratory evaluation is essential for the differentiation of benign lesions from primary malignant adrenal tumors or extra-adrenal metastasis.
Gittens, Paul R, Jr.+2 more
openaire +4 more sources
Pheochromocytoma is a tumor arising from neuroectodermal chromaffin tissues in the adrenal gland or extra-adrenal paraganglia (paragangliomas). The prevalence of the tumor is 0.1%-0.6% in the hypertensive population, of which 10%-20% are malignant ...
Alessadro Maloberti+10 more
doaj +1 more source
Listeria monocytogenes bacteremia mimicking the systemic metastasis of adrenal cancer: a case report
Background Listeria monocytogenes is a causative agent of food poisoning and is also known to cause invasive diseases, such as bacteremia, meningitis, and encephalitis, in neonates, elderly and immunocompromised patients.
Yuki Hatakeyama+8 more
doaj +1 more source
Introduction: treating benign (hormonally active or nonfunctional) and malignant adrenal cancer includes adrenalectomy. The expertise of surgeons and surgery performed by high-volume surgeons were associated with fewer complications and lower cost.
GUILHERME MIRANDA ANDRADE+9 more
doaj +2 more sources
Transrectal ultrasonography of the adrenal glands in donkeys (Equus asinus) [PDF]
Little information is available for medical imaging in donkeys and no report about adrenal glands ultrasonography can be found in scientific literature. The feasibility of transrectal ultrasonography of the adrenal glands was tested on 30 healthy donkeys
Cerquetella, Matteo+6 more
core +1 more source
Critical roles of endogenous glucocorticoids for disease tolerance in malaria
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien+4 more
core +1 more source