Results 91 to 100 of about 237,476 (293)

A Mouse Model of Depression‐Tumor Multimorbidity Reveals the Mechanism of Tumor Growth Accelerated by Depression

Animal Research and One Health, EarlyView.
Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren, Xinpei Wang, Wen Wang, Xingjiu Yang, Mengyuan Li, Jing Du, Ran Gao   +6 more
wiley   +1 more source

Endocrine system 4: adrenal glands

, 2021
The endocrine system consists of glands and tissues that produce and secrete hormones to regulate and coordinate vital bodily functions. This article, the fourth in an eight-part series on the endocrine system, explores the anatomy and physiology of the ...
John Knight, Zubeyde Bayram-Weston, Maria Andrade Sienz   +2 more
core  

A novel mutation L260P of the steroidogenic acute regulatory protein gene in three unrelated patients of swiss ancestry with congenital lipoid adrenal hyperplasia [PDF]

, 2005
Context: Lipoid congenital adrenal hyperplasia (CAH) is the most severe form of CAH leading to impaired production of all adrenal and gonadal steroids.
Maret, A, Achermann, J. C., Mullis, PE, Morel, Y., Leheup, B, Flück, Christa E., Portrat-Doyen, Stéphanie, Leheup, B., Achermann, JC, Mallet, D, Fluck, CE, Mullis, Primus-Eugen, Fluck, C. E., Maret, A., Morel, Yves, Mullis, P. E., Theintz, Gérald E., Portrat-Doyen, S., Theintz, GE, Leheup, Bruno, Mallet, D., Achermann, John C., Theintz, G. E., Morel, Y, Portrat-Doyen, S, Maret, Alexander, Mallet, Delphine   +26 more
core   +2 more sources

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Long-term follow-up in a Chinese child with congenital lipoid adrenal hyperplasia due to a StAR gene mutation

BMC Endocrine Disorders, 2018
Background Congenital lipoid adrenal hyperplasia (CLAH) is an extremely rare and the most severe form of congenital adrenal hyperplasia. Typical features include disorder of sex development, early-onset adrenal crisis and enlarged adrenal glands with ...
Xiu Zhao, Zhe Su, Xia Liu, Jianming Song, Yungen Gan, Pengqiang Wen, Shoulin Li, Li Wang, Lili Pan   +8 more
doaj   +1 more source

Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency [PDF]

, 2009
Context: Familial glucocorticoid deficiency (FGD) is an autosomal recessive disorder resulting from resistance to the action of ACTH on the adrenal cortex.
Racine, M, Naville, D., Nurnberg, G., Green, J, Metherell, L. A., Nurnberg, P, Krone, NP, Krone, N. P., Arlt, W, Tomlinson, Jeremy, Achermann, JC, Halaby, G, Tomlinson, J. W., Clark, A. J. L., Krone, Nils, Naville, D, Berney, D. M., Begeot, M., Huebner, A., Halaby, G., Green, J., Berney, DM, Clark, AJ, Lin, L, Lin, L., Racine, M., Arlt, Wiebke, Achermann, J. C., Arlt, W., Nurnberg, G, Metherell, LA, Tomlinson, JW, Begeot, M, Huebner, A, Nurnberg, P., Clark, AJL   +35 more
core   +1 more source

Primary Bilateral Non-Hodgkin's Lymphoma of the Adrenal Gland: A Case Report

Case Reports in Urology, 2012
Primary bilateral non-Hodgkin's lymphoma (NHL) of the adrenal gland is a very rare entity. Indeed less than 60 cases have been reported in the literature.
Ahmed Amine Bouchikhi, Mohamed fadl Tazi, Driss Amiroune, Soufiane Mellas, Jalaledine El Ammari, Abdelhak Khallouk, Mohammed Jamal El fassi, Moulay Hassan Farih   +7 more
doaj   +1 more source

DEVELOPMENT OF THE CORTICAL AND MEDULLARY CELLS OF ADRENAL GLAND IN THE LONG-TAILED MACAQUE (Macaca fascicularis) DURING PRE- AND POSTNATAL PERIOD

Jurnal Kedokteran Hewan, 2019
The study aimed to analyze the dynamics of the development of cortical and medullary cells of adrenal gland in the long-tailed macaque (Macaca fascicularis) during pre- and postnatal period. The samples of adrenal glands were taken from 5 fetuses aged 70,
Danang Dwi Cahyadi, Nurhidayat Nurhidayat, Supratikno Supratikno, Savitri Novelina, Chairun Nisa', Heru Setijanto   +5 more
doaj   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source

Anticipatory Stress in Medical Students Before Their First Cadaver Experience: A Physiological Component of Cadaver‐Based Anatomy Education

Clinical Anatomy, EarlyView.
ABSTRACT Cadaver‐based anatomy education represents a unique biological and sensory experience that may elicit significant physiological responses. However, little is known about the anticipatory phase prior to initial exposure, particularly when evaluated using objective biomarkers.
María Resino‐Rocha, Franscisco Gómez‐Esquer, Cecilia Peñacoba, Antonio Gil‐Crujera, Stella Maris Gómez‐Sánchez, Gema Díaz‐Gil   +5 more
wiley   +1 more source