Results 101 to 110 of about 807,614 (349)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

Diabetes mellitus remission in a cat with pituitary-dependent hyperadrenocorticism after trilostane treatment [PDF]

open access: yes, 2018
An 8-year-old male neutered Persian cat was presented with polyuria, polydipsia, polyphagia and muscle weakness associated with a 7 month history of diabetes mellitus (DM).
Adriana Cunha Muschner   +4 more
core   +3 more sources

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra   +4 more
wiley   +1 more source

A neuroanatomical basis for electroacupuncture to drive the vagal–adrenal axis

open access: yesNature, 2021
Shenbin Liu   +8 more
semanticscholar   +1 more source

Role of SoxE transcription factors in development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

DAMAGE TO THE ADRENAL GLANDS IN THE SIMULATION OF SUICIDE POISONING IN AN EXPERIMENT

open access: yesБайкальский медицинский журнал
Relevance. Suicidal poisonings occupy a special place among chemical poisonings, which occurs against the background of a previous psychotraumatic situation.
Vladimir G. Izatulin   +3 more
doaj   +1 more source

MANAGEMENT OF ADRENAL INCIDENTALOMA: THE POSITION STATEMENT OF THE CROATIAN REFERRAL CENTER FOR ADRENAL GLAND DISORDERS [PDF]

open access: yes, 2010
Incidentalomi nadbubrežne žlijezde jesu tumori otkriveni tijekom dijagnostičke evaluacije nekoga drugog kliničkog stanja. Tehnološki napredak radioloških uređaja i njihova sve veća upotreba u svakodnevnoj kliničkoj praksi doveli su do češćeg otkrivanja ...
DARKO KAŠTELAN   +15 more
core   +2 more sources

Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]

open access: yes, 2016
We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core   +2 more sources

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

open access: yesELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň   +3 more
wiley   +1 more source

Age related changes in the morphometric parameters of the Heart, Kidneys and Adrenal glands of Nili-Ravi buffalo (Bubalus bubalis)

open access: yesItalian Journal of Animal Science, 2010
Forty clinically healthy Nili-Ravi buffaloes (Bubalus bubalis) were divided into two age groups of 20 animals each viz., young (12-48 months of age) and adult (49-96 months) of each sex.
R. Hussain, A. Sarwar Qureshi
doaj   +1 more source

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