Results 291 to 300 of about 113,866 (372)

Angiosarcoma of the adrenal gland

open access: yesPolish Archives of Internal Medicine, 2013
Michał Holecki   +3 more
openaire   +3 more sources

Validation of target‐enriched enzymatic methylation sequencing for brain tumor classification from formalin‐fixed paraffin embedded‐derived DNA

open access: yesBrain Pathology, EarlyView.
Target‐enriched enzymatic methylation sequencing (TEEM‐seq), a DNA methylation sequencing method using the Twist Human Methylome panel, shows comparable performance to array‐based tumor methylation profiling. The method is compatible with both frozen and formalin‐fixed paraffin‐embedded (FFPE) samples and is a viable approach to tumor methylation and ...
Quynh T. Tran   +6 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Spatial Heterogeneity of PD‐L1 Expression as a Biomarker for Third‐Generation EGFR‐TKI Response in Advanced EGFR‐Mutant NSCLC

open access: yesCancer Science, EarlyView.
In advanced EGFR‐mutant NSCLC, high PD‐L1 expression may indicate reduced efficacy of third‐generation EGFR‐TKIs. PD‐L1 expression in primary lesions may serve as a prognostic marker, whereas expression in metastatic lymph nodes does not. This spatial heterogeneity could affect PD‐L1's predictive accuracy for third‐generation EGFR‐TKIs efficacy ...
Yidan Zhang   +7 more
wiley   +1 more source

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