Results 61 to 70 of about 807,614 (349)

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Myelolipomas of Both Adrenal Glands

Korean Journal of Urology, 2011
Adrenal myelolipoma is a rare, nonfunctional benign tumor that is composed of mature adipose tissue and hematopoietic elements. In the past, these tumors were accidentally discovered at autopsy. Today, they are found much more frequently and incidentally,
Jai Seong Cha, Y. Shin, M. Kim, H. J. Kim   +3 more
semanticscholar   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Neuroma embryonic sympathetic - Neuroblastoma. Review of the literature

Journal of Education, Health and Sport, 2017
Embryonic Neuroma sympathetic is derived from nerve cells, of which during normal development are sympathetic ganglia and the adrenal Medulla. Primary outbreak is found for this reason along the axis of the body - in the pelvis, retroperitoneal, bone ...
Agnieszka Budny, Jakub Litak, Cezary Grochowski   +2 more
doaj   +3 more sources

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Adrenal gland infection by serotype 5 adenovirus requires coagulation factors. [PDF]

PLoS ONE, 2013
Recombinant, replication-deficient serotype 5 adenovirus infects the liver upon in vivo, systemic injection in rodents. This infection requires the binding of factor X to the capsid of this adenovirus.
Lucile Tran, Laure-Hélène Ouisse, Peggy Richard-Fiardo, Philippe R Franken, Jacques Darcourt, Gaétan Cornilleau, Karim Benihoud, Georges Vassaux   +7 more
doaj   +1 more source

Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II [PDF]

, 1994
By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes ...
Baekkeskov S., Banga J. P., Bernhard O. Boehm, Betterle C. F., Bjork E., Bottazzo G. F, Bottazzo G. F., Christie M. R., Genovese S., Hagopan W. A., Jochen Seissler, Karlsen A. E., Kawasaki E., Kim J., Ludwig Mauch, Mauch L., Muir A., Nadja Yassin, Richter W., Riley W. J., Sabine Bieg, Scherbaum W. A, Scherbaum W. A., Schmidli R TS, Seissler J., Solimena M., Tarn A. C., Ujihara N., Velloso L. A., Wagner R., Wagner R., Werner A. Scherbaum, Wolfgang Northemann   +32 more
core   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

Primary bilateral non-Hodgkin's lymphoma of the adrenal gland

Indian Journal of Urology, 2018
Primary bilateral non-Hodgkin's lymphoma (NHL) of the adrenal gland is very rare. Herein, we report the case of a high-grade lymphoma of both adrenal glands that was found in a 38-year-old patient.
Mohammad Raoofziaee, Aliasghar Yarmohamadi, Hassan Ahmadnia   +2 more
doaj   +1 more source

Distribution of intravenously administered acetylcholinesterase inhibitor and acetylcholinesterase activity in the adrenal gland: 11C-donepezil PET study in the normal rat. [PDF]

PLoS ONE, 2014
PURPOSE: Acetylcholinesterase (AChE) inhibitors have been used for patients with Alzheimer's disease. However, its pharmacokinetics in non-target organs other than the brain has not been clarified yet.
Tadashi Watabe, Sadahiro Naka, Hayato Ikeda, Genki Horitsugi, Yasukazu Kanai, Kayako Isohashi, Mana Ishibashi, Hiroki Kato, Eku Shimosegawa, Hiroshi Watabe, Jun Hatazawa   +10 more
doaj   +1 more source