Results 61 to 70 of about 251,940 (297)

Adrenal gland infection by serotype 5 adenovirus requires coagulation factors. [PDF]

open access: yesPLoS ONE, 2013
Recombinant, replication-deficient serotype 5 adenovirus infects the liver upon in vivo, systemic injection in rodents. This infection requires the binding of factor X to the capsid of this adenovirus.
Lucile Tran   +7 more
doaj   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

open access: yesAdvanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan   +14 more
wiley   +1 more source

Study of morphological alterations of the adrenal glands in the neoplastic cachexia
Estudo das alterações morfológicas da glândula adrenal na caquexia neoplásica

open access: yesSemina: Ciências Biológicas e da Saúde, 2009
Advanced cancer occurs with nutritional and metabolic alterations that characterize neoplastic cachexia. When homeostasis is compromised, the adrenal glands have a fundamental role in the neuroendocrine response. Our purpose in this research was to study
Tânia Longo Mazzuco   +4 more
doaj  

Three-dimensional Volumetric Ultrasonography of Enlarged Adrenal Gland in Dog [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2011
Objective: Detection and evaluation of adrenal glands are complex problems in conventional ultrasonography in dogs. Using three-dimensional (3D) ultrasonography (US) in adrenal gland volume evaluation can add new potential for further adrenal studies ...
Shaghayegh Asadi   +5 more
doaj  

Distribution of intravenously administered acetylcholinesterase inhibitor and acetylcholinesterase activity in the adrenal gland: 11C-donepezil PET study in the normal rat. [PDF]

open access: yesPLoS ONE, 2014
PURPOSE: Acetylcholinesterase (AChE) inhibitors have been used for patients with Alzheimer's disease. However, its pharmacokinetics in non-target organs other than the brain has not been clarified yet.
Tadashi Watabe   +10 more
doaj   +1 more source

Enlightening the adrenal gland [PDF]

open access: yesCell Metabolism, 2005
The secretion of glucocorticoid hormones is tightly regulated by the circadian clock and by negative humoral feedback loops, both acting on the hypothalamic-pituitary gland-adrenal axis. However, a new study Ishida et al., 2005 [this issue of Cell Metabolism) shows that light can influence the adrenal's glucocorticoid output by a more direct pathway.
Schibler, Ulrich, Brown, Steven
openaire   +3 more sources

The Effects Of Experimentally İnduced İntraabdominal Hypertension On Adrenal Glands

open access: yes, 2012
Conclusion: The effects of experimental IAH on adrenal glands were statistically significant. The alterations of the adrenal glands could be the result of the direct effects of IAH, which is a severe trauma for the organ, or could be the effects of other
Gokturk Maralcan   +17 more
core   +1 more source

Hypothalamic POMC Neurons Gate the Fear‐Feeding Trade‐Off

open access: yesAdvanced Science, EarlyView.
Hungry animals must continually arbitrate between feeding and defensive behaviors when confronted with potential threats. We show that hypothalamic POMC neurons engage CRH‐expressing stress circuits and downstream hormonal responses to coordinate this behavioral selection between competing behaviors.
Cristina Miralpeix   +16 more
wiley   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

open access: yesAdvanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim   +12 more
wiley   +1 more source

Primary hyperaldosteronism: challenges in subtype classification

open access: yesBMC Research Notes, 2012
Background Primary hyperaldosteronism (PA) is a serious and potentially debilitating disease. Detailed guidelines have been written to guide endocrinologists in establishing the diagnosis of PA as well as in subtype classification of PA. The objective of
Layden Brian T   +2 more
doaj   +1 more source

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