Results 51 to 60 of about 68,585 (298)

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

open access: yesAdvanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma   +10 more
wiley   +1 more source

A: CAR expression in the liver and the adrenal glands. [PDF]

open access: yes, 2013
Total RNAs were extracted from liver biopsies or total adrenal glands and subjected to reverse transcription and PCR amplification. The PCR products were separated by electrophoresis. B and C: Mice were injected systemically with 109 PFU of either AdHwt (
Jacques Darcourt (329004)   +7 more
core   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

ULTRASTRUCTURAL PROPERTIES OF THE ADRENAL GLANDS DURING THE ACUTE HYPOXIA [PDF]

open access: yes, 2019
The goal of the study was to study the morphofunctional properties of ultrastructural changes in the cellular and extracellular structures of the adrenal glands during hypobaric hypoxia. The materials of the study were 30 male white rats weighing 180-200
Mammadhasan, Y. S. (Yagubova)   +1 more
core   +2 more sources

ELECTRON MICROSCOPIC CHANGES IN THE CELLULAR AND EXTRACELLULAR STRUCTURES OF THE ADRENAL AND THYROID GLANDS DURING ACUTE HYPOXIA

open access: yesПаёми Сино, 2019
Objective: To study the morphofunctional features of ultrastructural changes in the cellular and extracellular structures of adrenal and thyroid glands during acute hypoxia.
S.M. YAGUBOVA
doaj   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña   +7 more
wiley   +1 more source

Chrysin’s dose-dependent effects on steroidogenesis in female BALB/c mice: In vivo study of adrenal, ovarian, and uterine hormone regulation [PDF]

open access: yesPharmacia
Background: Chrysin is known for its pharmacological effects and structural resemblance to estrogen. The study explores the impact of chrysin on steroidogenesis focusing on adrenal and ovarian steroidogenic enzymes.
Khalid M. Alqaisi   +2 more
doaj   +3 more sources

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

open access: yesAdvanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes   +15 more
wiley   +1 more source

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

open access: yesAdvanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae   +27 more
wiley   +1 more source

Neuroma embryonic sympathetic - Neuroblastoma. Review of the literature

open access: yesJournal of Education, Health and Sport, 2017
Embryonic Neuroma sympathetic is derived from nerve cells, of which during normal development are sympathetic ganglia and the adrenal Medulla. Primary outbreak is found for this reason along the axis of the body - in the pelvis, retroperitoneal, bone ...
Agnieszka Budny   +2 more
doaj   +3 more sources

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