Results 111 to 120 of about 423,582 (318)

The experience of women living with Congenital Adrenal Hyperplasia: impact of the condition and the care given

open access: yesClinical Endocrinology, 2016
Congenital adrenal hyperplasia (CAH) is caused most often by mutations in the CYP21A2 gene, resulting in cortisol and aldosterone deficiency and increased production of androgens.
Hedvig Engberg   +4 more
semanticscholar   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak   +4 more
wiley   +1 more source

A boy or a girl? : Parental, family and whanau information needs when a child is born with an intersex/DSD condition : a thesis presented in fulfilment of the requirements for the degree of MPHIL in Nursing at Massey University, Auckland, New Zealand [PDF]

open access: yes, 2008
Is it a girl or a boy? This is a question that new parents assume will be answered at the birth, or even in the months leading up to the birth of their baby.
McCarthy, Gabrielle Leigh
core  

The ACTH test in the diagnosis of hirsutism

open access: yesSão Paulo Medical Journal
The ACTH test has been used to confirm the diagnosis of adrenal insufficiency and the classic and the non-classic adrenal hyperplasia due to the 3-HSD, 21 OH e 110H deficiencies.
Marco Fábio Prata Lima   +5 more
doaj   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

A case of Cushing's syndrome undergone bilateral subtotal adrenalectomy [PDF]

open access: yes, 1967
A 58 years old house wife visited our hospital complaining of obesity and hypertension. A diagnosis of Cushing's syndrome due to adrenal hyperplasia was made based on results of various examinations, and the patient was operated on subtotal bilateral ...
伊藤, 千賀子   +3 more
core  

A rare case report of hypertrophic cardiomyopathy induced by catecholamine-producing tumor [PDF]

open access: yes, 2018
RATIONALE: Catecholamine-producing tumors are rare, occurring in less than 0.2% of patients with hypertension, but can have relevant cardiovascular morbidity and mortality. PATIENT CONCERNS: A 37-year-old woman presented with a history of dyspnea, chest
Bisogni, Valeria   +12 more
core   +1 more source

ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2015
CONTEXT Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of primary adrenal Cushing's syndrome (CS). ARMC5 germline mutations have been identified recently in PBMAH. OBJECTIVE To determine the prevalence of ARMC5 mutations and
S. Espiard   +22 more
semanticscholar   +1 more source

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

open access: yesCell Proliferation, EarlyView.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng   +10 more
wiley   +1 more source

Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2015
CONTEXT Primary macronodular adrenal hyperplasia (PMAH) is a rare cause of Cushing's syndrome, which may present in the context of different familial multitumor syndromes.
U. Elbelt   +14 more
semanticscholar   +1 more source

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