Results 71 to 80 of about 423,582 (318)
The Journal of Pathology, EarlyView.Abstract Lung cancer is the leading cause of cancer‐related death globally. To better understand the biology of lung cancer, mouse models have been developed using either tail vein‐injected tumour cell lines or genetically modified mice. The current gold‐standard models typically present with multiple lung foci.
Ana‐Rita Pedrosa +20 more
wiley +1 more source
Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
Cell Reports, 2020 Summary: Activating mutations in the canonical Wnt/β-catenin pathway are key drivers of hyperplasia, the gateway for tumor development. In a wide range of tissues, this occurs primarily through enhanced effects on cellular proliferation.
Emanuele Pignatti +12 more
doaj
UroPrecision, EarlyView.Abstract Background Adrenal tumor is a common condition that often requires adrenalectomy. The objective of this study is to compare the safety and implementation of the enhanced recovery after surgery (ERAS) among patients who received open, laparoscopic and robotic‐assisted operation.
Bingfeng Luo +7 more
wiley +1 more source
The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood [PDF]
, 1973 The hepatotrophic factors previously reported to be in splanchnic venous blood are pancreatic hormones and specifically insulin and glucagon. Of these, insulin is anabolic and glucagon is mainly catabolic but not exclusively so, since glucagon also has ...
Brown, TH +6 more
core
2D:4D Suggests a Role of Prenatal Testosterone in Gender Dysphoria [PDF]
, 2020 Gender dysphoria (GD) reflects distress caused by incongruence between one’s experienced gender identity and one’s natal (assigned) gender. Previous studies suggest that high levels of prenatal testosterone (T) in natal females and low levels in natal ...
Fazeli, Nasrin +4 more
core +2 more sources
Syrian females with congenital adrenal hyperplasia: a case series
Journal of Medical Case Reports, 2022 Background One of the most common types of congenital adrenal hyperplasia is an autosomal recessive disorder with 21-hydroxylase deficiency. The classical form, defined by cortisol insufficiency, is accompanied by prenatal androgen excess causing ...
Nada Dehneh +4 more
doaj +1 more source
Genetics in Medicine, 2017 PurposeNonclassic 21-hydroxylase deficiency, a mild form of congenital adrenal hyperplasia (CAH), is estimated to be the most common autosomal recessive condition, with an especially high prevalence in Ashkenazi Jews (3.7% affected, 30.9% carriers ...
Fady Hannah-Shmouni +7 more
semanticscholar +1 more source
Veterinary Record Case Reports, EarlyView.Abstract This report describes a case of refractory ionised hypercalcaemia, of 12 months duration, in an 11‐year‐old, male, neutered beagle diagnosed with metastatic histiocytic sarcoma at postmortem examination. In this case, the parathyroid hormone levels were at the lower end of the reference interval, the parathyroid hormone‐related peptide was ...
Kerry E. Rolph +5 more
wiley +1 more source
, 2019 Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik +2 more
core +1 more source
Screening for Mutations of 21-Hydroxylase Gene in Hungarian Patients with Congenital Adrenal Hyperplasia [PDF]
, 1999 Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders, causing impaired secretion of cortisol and aldosterone from the adrenal cortex, with subsequent overproduction of adrenal androgens.
Barta, Csaba +8 more
core +1 more source