Results 41 to 50 of about 3,076 (170)
ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley +1 more source
Hypercortisolism: An Under‐Recognised Pathway Linked to Multi‐System Complications
ABSTRACT The clinical understanding of hypercortisolism (HC) has evolved from a classic overt syndrome with florid Cushingoid features to a broader spectrum of disease that includes milder presentations, often referred to as mild autonomous cortisol secretion (MACS).
Hernan Daniel Sacoto, Vivian A. Fonseca
wiley +1 more source
ABSTRACT Aim To provide a practical guide on when to suspect endogenous hypercortisolism, how to use the overnight 1‐mg dexamethasone suppression test (DST) for targeted case‐finding, and which patients are most likely to benefit from treatment.
Juan Pablo Frias
wiley +1 more source
ABSTRACT Importance Hypercortisolism is an underdiagnosed contributor to metabolic dysfunction in people with Type 2 diabetes (T2D). Although overt Cushing syndrome is rare, milder forms of cortisol excess, commonly termed mild autonomous cortisol secretion (MACS), appear substantially more common in selected high‐risk populations. Observations Chronic
Jenine Yager Stone, Timothy S. Bailey
wiley +1 more source
Lipid Profile in Primary Aldosteronism: Cross‐Sectional and Post‐Treatment Analyses
ABSTRACT The relationship between primary aldosteronism (PA) and lipid metabolism remains controversial, with inconsistent findings reported in the literature. This study aimed to clarify PA's impact on the lipid profile using both a cross‐sectional comparison with essential hypertension (EH) controls and a longitudinal within‐patient pre‐post ...
Meriem Yazidi +7 more
wiley +1 more source
A Rare Adrenal Incidentaloma That Mimics Adrenocortical Carcinoma
Objective. We present a case of an adrenal hemangioma, an uncommon cause of an adrenal mass, and review the clinical presentation, work-up, and management of adrenal incidentalomas. Background.
Kedar Lavingia +5 more
doaj +1 more source
Schwannomas are rare tumors, usually benign, originating from the Schwann sheath of the peripheral or cranial nerves. They are an extremely uncommon cause of adrenal incidentaloma.
Houda Salhi +4 more
doaj +1 more source
Diffuse and Prolonged Bone Pain Revealing Tumor‐Induced Osteomalacia: A Case Report
ABSTRACT Tumor‐induced osteomalacia should be considered in patients with unexplained bone pain and fractures. Advanced imaging, such as Ga68‐DOTATATE PET/CT, enables precise tumor localization, and surgical excision can rapidly normalize phosphate metabolism and resolve symptoms, underscoring the importance of early diagnosis and intervention.
Rahman Amraei +3 more
wiley +1 more source
Not So Incidental: Pheochromocytoma in an Adult with Unrepaired Cyanotic Heart Disease
Pheochromocytoma, a rare neuroendocrine tumour, is often encountered in the general internal medicine clinic as an adrenal incidentaloma. Even rarer is its presence in adult cyanotic heart disease, although there are a few documented reports of this ...
Nikesh Adunuri, Marko Mrkobrada
doaj +1 more source
A Circadian Trough in Glucocorticoid Signaling Is Essential for Bone Health in Mice
Flattening the circadian rhythm of endogenous glucocorticoids induces osteoporosis in mice. We demonstrate that reinstating a trough in glucocorticoid receptor signaling stimulates bone formation and suffices to prevent osteoporosis. Reinstating the trough at its natural time of day is needed for full protection.
Annelies E. Smit +9 more
wiley +1 more source

