Results 1 to 10 of about 34,910 (200)

Rare Association Between Neurofibromatosis Type 1 and Adrenocortical Carcinoma [PDF]

Clinical Case Reports
Although rare, adrenocortical carcinoma (ACC) should be considered in individuals with neurofibromatosis type 1 (NF1) presenting with adrenal incidentalomas.
Zachary Pluim, Joseph Do Woong Choi, Benedict Kakala, Jessica Wong, Roderick Clifton‐Bligh, Mark Sywak, Julie Howle   +6 more
doaj   +2 more sources

Pediatric adrenocortical carcinoma

Frontiers in Endocrinology, 2022
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy of the adrenal gland with an unfavorable prognosis. It is rare in the pediatric population, with an incidence of 0.2-0.3 patients per million in patients under 20 years old.
Maran Ilanchezhian, Diana Grace Varghese, John W. Glod, Karlyne M. Reilly, Brigitte C. Widemann, Yves Pommier, Rosandra N. Kaplan, Jaydira Del Rivero   +7 more
doaj   +3 more sources

Adrenocortical Carcinoma [PDF]

Cancers, 2021
Adrenocortical carcinoma (ACC) is an extremely rare disease, the incidence of which is 0 [...]
Berruti A., Tiberio G. A. M., Sigala S.
  +7 more sources

A hypoxia risk score for prognosis prediction and tumor microenvironment in adrenocortical carcinoma

Frontiers in Genetics, 2022
Background: Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumor derived from the adrenal cortex. Because of its highly aggressive nature, the prognosis of patients with adrenocortical carcinoma is not impressive. Hypoxia exists in the vast
Yuanyuan Deng, Huihuang Li, Jinglan Fu, Ying Pu, Ying Zhang, Shijing Chen, Shiyu Tong, Huixia Liu   +7 more
doaj   +1 more source

DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggressiveness of adrenocortical carcinoma

Clinical Epigenetics, 2023
Background Adrenocortical carcinoma is rare and aggressive endocrine cancer of the adrenal gland. Within adrenocortical carcinoma, a recently described subtype characterized by a CpG island methylator phenotype (CIMP) has been associated with an ...
Gwenneg Kerdivel, Floriane Amrouche, Marie-Ange Calmejane, Floriane Carallis, Juliette Hamroune, Constanze Hantel, Jérôme Bertherat, Guillaume Assié, Valentina Boeva   +8 more
doaj   +1 more source

Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R [PDF]

, 2013
Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the
Bertherat, Jérôme, Beuschlein, Felix, Bonnet, Stéphane, Gaujoux, Sébastien, Guillaud-Bataille, Marine, Hantel, Constanze, Launay, Pierre, Lefèvre, Lucile, Perlemoine, Karine, Ragazzon, Bruno, Rizk-Rabin, Marthe, Tissier, Frédérique   +11 more
core   +12 more sources

Adrenocortical Carcinoma [PDF]

Endocrine Reviews, 2013
AbstractAdrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable prognosis. Here we summarize the knowledge about diagnosis, epidemiology, pathophysiology, and therapy of ACC. Over recent years, multidisciplinary clinics have formed and the first international treatment trials have been conducted.
Tobias, Else, Alex C, Kim, Aaron, Sabolch, Victoria M, Raymond, Asha, Kandathil, Elaine M, Caoili, Shruti, Jolly, Barbra S, Miller, Thomas J, Giordano, Gary D, Hammer   +9 more
openaire   +2 more sources

Adrenocortical carcinoma with inferior vena cava tumor thrombus found during surgery

IJU Case Reports, 2022
Introduction The safety and efficacy of minimally invasive approaches for adrenocortical carcinoma with inferior vena cava tumor thrombus have not yet been established.
Yuta Nabeshima, Shimpei Yamashita, Ryusuke Deguchi, Ryuta Iwamoto, Kenji Warigaya, Hiroyuki Koike, Kazuro Kikkawa, Yasuo Kohjimoto, Shinichi Murata, Isao Hara   +9 more
doaj   +1 more source

Generation and characterization of a mitotane-resistant adrenocortical cell line [PDF]

, 2020
Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy.
Bachmann, Sebastian, Bahethi, Rohini, Beule, Dieter, Choi, Murim, Eisenhofer, Graeme, Liebisch, Gerhard, Messerschmidt, Clemens, Obermayer, Benedikt, Peitzsch, Mirko, Scholl, Ute I., Schrade, Petra, Seidel, Eric, Walenda, Gudrun, Wallace, Paal, Yoo, Taekyeong   +14 more
core   +2 more sources

The diagnosis and treatment of adrenocortical carcinoma in pregnancy: a case report

BMC Pregnancy and Childbirth, 2020
Background Pregnancy complicated with adrenocortical carcinoma (ACC) is a sporadic syndrome that is characterized by hypertension, uncontrolled hypokalemia, severe heart failure, premature delivery and other adverse effects.
Yuanli Zhang, Zeng Yuan, Chunping Qiu, Shuyi Li, Shiqian Zhang, Yan Fang   +5 more
doaj   +1 more source