Results 1 to 10 of about 22,616 (177)

Rare Association Between Neurofibromatosis Type 1 and Adrenocortical Carcinoma [PDF]

Clinical Case Reports
Although rare, adrenocortical carcinoma (ACC) should be considered in individuals with neurofibromatosis type 1 (NF1) presenting with adrenal incidentalomas.
Zachary Pluim, Joseph Do Woong Choi, Benedict Kakala, Jessica Wong, Roderick Clifton‐Bligh, Mark Sywak, Julie Howle   +6 more
doaj   +2 more sources

A hypoxia risk score for prognosis prediction and tumor microenvironment in adrenocortical carcinoma

Frontiers in Genetics, 2022
Background: Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumor derived from the adrenal cortex. Because of its highly aggressive nature, the prognosis of patients with adrenocortical carcinoma is not impressive. Hypoxia exists in the vast
Yuanyuan Deng, Huihuang Li, Jinglan Fu, Ying Pu, Ying Zhang, Shijing Chen, Shiyu Tong, Huixia Liu   +7 more
doaj   +1 more source

DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggressiveness of adrenocortical carcinoma

Clinical Epigenetics, 2023
Background Adrenocortical carcinoma is rare and aggressive endocrine cancer of the adrenal gland. Within adrenocortical carcinoma, a recently described subtype characterized by a CpG island methylator phenotype (CIMP) has been associated with an ...
Gwenneg Kerdivel, Floriane Amrouche, Marie-Ange Calmejane, Floriane Carallis, Juliette Hamroune, Constanze Hantel, Jérôme Bertherat, Guillaume Assié, Valentina Boeva   +8 more
doaj   +1 more source

Adrenocortical carcinoma with inferior vena cava tumor thrombus found during surgery

IJU Case Reports, 2022
Introduction The safety and efficacy of minimally invasive approaches for adrenocortical carcinoma with inferior vena cava tumor thrombus have not yet been established.
Yuta Nabeshima, Shimpei Yamashita, Ryusuke Deguchi, Ryuta Iwamoto, Kenji Warigaya, Hiroyuki Koike, Kazuro Kikkawa, Yasuo Kohjimoto, Shinichi Murata, Isao Hara   +9 more
doaj   +1 more source

The diagnosis and treatment of adrenocortical carcinoma in pregnancy: a case report

BMC Pregnancy and Childbirth, 2020
Background Pregnancy complicated with adrenocortical carcinoma (ACC) is a sporadic syndrome that is characterized by hypertension, uncontrolled hypokalemia, severe heart failure, premature delivery and other adverse effects.
Yuanli Zhang, Zeng Yuan, Chunping Qiu, Shuyi Li, Shiqian Zhang, Yan Fang   +5 more
doaj   +1 more source

Extra-adrenal, non-functional adrenocortical carcinoma presenting with acute abdomen: a case report

Journal of Medical Case Reports, 2020
Background Adrenocortical carcinoma is a rare malignancy, with 43% being non-functional. These may arise from adrenal rest anywhere in the embryonic pathway of the adrenal glands.
Alireza Mirsharifi, Mohammad Vasei, Ehsan Sadeghian, Ali Ghorbani-Abdehgah, Sara Naybandi Atashi   +4 more
doaj   +1 more source

A case of estrogen‐secreting adrenocortical carcinoma: Comprehensive immunohistochemical analysis of disorganized steroid genesis

IJU Case Reports, 2021
Introduction Adrenocortical carcinoma rarely secretes estrogens, and little is known regarding the mechanism of intra‐tumor estrogen production. We report an estrogen‐secreting adrenocortical carcinoma in a postmenopausal woman, where comprehensive ...
Megumi Yokoyama, Toshiki Kijima, Atsuko Takada‐Owada, Kazumasa Sakamoto, Issei Suzuki, Daisaku Nishihara, Yasuhiro Nakamura, Kazuyuki Ishida, Takao Kamai   +8 more
doaj   +1 more source

Estrogen-secreting adrenocortical carcinoma [PDF]

Yeungnam University Journal of Medicine, 2019
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete aldosterone or androgen.
You Jeong, Sung Chul Cho, Hee Joon Cho, Ji Soo Song, Joon Seog Kong, Jong Wook Park, Yun Hyi Ku   +6 more
doaj   +1 more source

Pitfalls and progress in adrenocortical carcinoma diagnosis: the utility of a multidisciplinary approach, immunohistochemistry and genomics

Endocrinology, Diabetes & Metabolism Case Reports, 2022
Adrenocortical carcinoma is a rare disease with poor prognosis whose clinical heterogeneity can at times present a challenge to accurate and timely diagnosis.
Ray Wang, Benjamin Solomon, Stephen J Luen, Owen W.J. Prall, Christine Khoo, Anthony J Gill, Jeremy Lewin, Nirupa Sachithanandan   +7 more
doaj   +1 more source

Venous thromboembolism in patients with adrenocortical carcinoma after surgery

Endocrine Connections, 2020
Background: Adrenocortical carcinoma is a rare malignancy with a poor prognosis. We hypothesized that patients with adrenocortical carcinoma are at high risk for venous thromboembolism, given the numerous risk factors such as malignancy, abdominal ...
Jülide Durmuşoğlu, Henri J L M Timmers, Pepijn van Houten, Hans F Langenhuijsen, Ad R M M Hermus, Annenienke C van de Ven   +5 more
doaj   +1 more source