Results 31 to 40 of about 22,616 (177)

Ectopic adrenocortical adenoma in the renal hilum mimicking a renal cell carcinoma

Radiology Case Reports, 2022
Ectopic adrenocortical tissue can arise along the path of embryonic migration, such as the celiac axis, broad ligament, adnexa of the testis, and spermatic cord.
Masashi Endo, MD, Hiroyuki Fujii, MD, PhD, Akifumi Fujita, MD, PhD, Tatsuya Takayama, MD, PhD, Daisuke Matsubara, MD, PhD, Tomohiro Kikuchi, MD, Saki Manaka, MD, Harushi Mori, MD, PhD   +7 more
doaj   +1 more source

Robot-Assisted Laparoscopic Adrenalectomy for Rare Myxoid Adrenocortical Carcinoma

Case Reports in Urology, 2019
Background. Surgical resection remains the standard treatment for adrenocortical carcinoma. Higher rates of local and peritoneal recurrence have been reported with the laparoscopic approach compared to open resection, although the evidence is limited.
Grant Johnson, Kiran Thalody, Umesh Kapur, Thai T. Nguyen   +3 more
doaj   +1 more source

Long‐term survival of a patient with refractory advanced adrenocortical carcinoma after combination chemotherapy with paclitaxel and carboplatin plus mitotane

IJU Case Reports, 2022
Introduction The prognosis of patients with unresectable adrenocortical carcinoma is poor. Mitotane is the first‐line treatment for this disease, and etoposide/doxorubicin/cisplatin/mitotane therapy is recommended as first‐line chemotherapy in ...
Yuki Kobayakawa, Shuzo Hamamoto, Hideyuki Kamisawa, Shinsuke Okada, Kazumi Taguchi, Taku Naiki, Atsushi Okada, Keiichi Tozawa, Takahiro Yasui   +8 more
doaj   +1 more source

Medical Approaches in Adrenocortical Carcinoma [PDF]

Biomedicines, 2020
Adrenocortical carcinoma (ACC) represents one of the most aggressive endocrine tumors. In spite of a correct therapeutic strategy based on a multidisciplinary approach between endocrinologist, surgeon and oncologist, the prognosis is often poor. Surgery is the mainstay treatment in ACC.
Paragliola R. M., Corsello A., Locantore P., Papi G., Pontecorvi A., Corsello S. M.   +5 more
openaire   +4 more sources

Adrenocortical Carcinoma Presenting with Signs of Acute Abdomen

Case Reports in Surgery, 2013
Background. Adrenocortical carcinomas represent rare malignancies. In cases of hormone-secreting tumors, the hormone in excess determines the nearly diagnostic clinical presentation.
Dimitrios Symeonidis, Ioannis Chatzinikolaou, Georgios Koukoulis, Ioannis Mamaloudis, Konstantinos Tepetes   +4 more
doaj   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

An Excellent Clinical and Radiological Response Pattern to Pembrolizumab in a Patient With Metastatic Adrenocortical Carcinoma and Lynch Syndrome

IJU Case Reports
Introduction The prognosis of unresectable metastatic adrenocortical carcinoma is very poor. We report a case of Lynch syndrome accompanying metastatic adrenocortical carcinoma treated with pembrolizumab.
Yuki Shimozawa, Yosuke Yasuda, Emiko Sugawara, Ryosuke Oki, Kosuke Takemura, Tetsuya Urasaki, Ryo Fujiwara, Noboru Numao, Junji Yonese, Takeshi Yuasa   +9 more
doaj   +1 more source

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang, Qian Wang, Xiumei Jiang, Yongmei Yang, Ailin Qu   +4 more
wiley   +1 more source

Efficacy of oral metformin in a patient with metastatic adrenocortical carcinoma: Examination of mechanisms and therapeutic implications

Rare Tumors, 2018
Although rare, adrenocortical carcinoma is among the most common tumors found in children with Li-Fraumeni syndrome and Li-Fraumeni-like syndrome, associated with germ-line mutations in the TP53 gene. In southern Brazil, one form of Li-Fraumeni syndrome,
RD Peixoto, LM Gomes, TT Sousa, DJ Racy, M Shigenaga, RA Nagourney   +5 more
doaj   +1 more source