Results 141 to 150 of about 221,430 (290)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

Journal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino, Samantha Dockray, Maria Dempsey, Eleonora Tomei   +3 more
wiley   +1 more source

Nanoplastics: Methods, Exposure and Effects on Domestic, Farm and Wild Animals

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are synthetic polymer particles ranging in size from 1 nm to 1 μm that have been identified as a major concern for ecosystems and organisms due to their plethora of negative effects. The aim of this review is to provide a comprehensive overview of the knowledge relating to exposure and effects of NPs in domestic (i.e., farm ...
B. De Felice, M. Bertazzo, A. F. Tabaran, M. Parolini, R. P. Popa, A. Pintea, L. J. Spicer, A‐L. Nagy, F. Caloni   +8 more
wiley   +1 more source

Patient Centring in CT: An International Survey of Clinical Practice and Future Directions

Journal of Medical Radiation Sciences, EarlyView.
An international survey of 321 radiographers from 43 countries found vertical mis‐centring below the CT isocentre is the most frequent positioning error. Only 34% had access to automated centring systems and 17% used them consistently. Substantial knowledge gaps exist regarding radiation dose and CT number variability, highlighting the need for ...
Yasser H. Hadi, Mo'men Bani‐Ahmad, Niamh Moore, Kevin R. Clark, Yazan Al‐Hayek, Salman M. Albeshan, Sultan B. Alghamdi, Helle Precht, Andrew England, Mark McEntee   +9 more
wiley   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala, Madeline Carr, Yolanda Surjan, Parmoun Daghigh, Jeremy de Leon, Abbey Burns, Vikneswary Batumalai   +6 more
wiley   +1 more source

Acute adrenal insufficiency: Optimising care

, 2018
Adrenal crises are severe, life-threatening episodes of adrenal insufficiency. Preventing and managing adrenal crises is complex and current strategies have not been successful in achieving a reduction in the incidence of episodes.
Falhammar, Henrik, Rushworth, R Louise, Torpy, David J   +2 more
core   +1 more source

Understanding and Addressing Delays in Endocrine Surgery: Insights From a Mixed‐Methods Study and a Pilot Educational Intervention

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Delays in endocrine surgical care contribute to adverse events, patient dissatisfaction, and mortality. Communication is an overlooked contributor. This study identified multi‐level drivers of delay and piloted a provider‐focused intervention. Methods We conducted an IRB‐approved mixed‐methods study.
Stella Kim, Maxwell Foote, Sophia Zhang, Audrey Twyford, Abigail Fox, Jennifer E. Rosen   +5 more
wiley   +1 more source

Perioperative Risks of Concurrent Pancreatic and Hepatic Resections for Neuroendocrine Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Pancreatic neuroendocrine tumors (pNETs) account for 1%–2% of pancreatic tumors, with an increasing incidence. The safety of concurrent pancreas‐liver resections remains uncertain. This study evaluated the national outcomes of concurrent pancreatectomy and liver‐directed surgery for pNETs. Methods ACS‐NSQIP (2019–2023)
Amir Ebadinejad, Ashrita Raghuram, Sophia Xiao, Ethan Angle, Hassan Aziz   +4 more
wiley   +1 more source

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

Medicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang, Wen‐Bi He, Fei‐Peng Chen, Jiong‐Xing Huang, Lin Zhu, Xiao‐Guang Liu   +5 more
wiley   +1 more source