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OBSERVATIONS ON ADRENAL INSUFFICIENCY [PDF]
Journal of Clinical Investigation, 1936 Jules Stahl +2 more
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The Lancet, 2003 Adrenal insufficiency is caused by either primary adrenal failure (mostly due to autoimmune adrenalitis) or by hypothalamic-pituitary impairment of the corticotropic axis (predominantly due to pituitary disease). It is a rare disease, but is life threatening when overlooked.
Deana Kenward, Katherine White
+5 more sources
Tests of adrenal insufficiency [PDF]
Archives of Disease in Childhood, 1999 In suspected adrenal insufficiency, the ideal test for assessing the hypothalamo-pituitary-adrenal axis is controversial. Therefore, three tests were compared in patients presenting with symptoms suggestive of adrenal insufficiency.Responses to the standard short Synacthen test (SSST), the low dose Synacthen test (LDST), and the 08:00 hour serum ...
Juliana Chizo Agwu +4 more
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Clinical Medicine, 2008 In 1855, Thomas Addison identified a clinical syndrome characterized by wasting and hyperpigmentation as the result of adrenal gland destruction (1). This landmark observation paved the way for progress in understanding and treating adrenal insufficiency, with the introduction of adrenal extracts for treatment of Addison’s disease by the groups of ...
openaire +3 more sources
The Lancet, 2014 Adrenal insufficiency is the clinical manifestation of deficient production or action of glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens. It is a life-threatening disorder that can result from primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic-pituitary axis.
Evangelia, Charmandari +2 more
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Case Reports in Psychiatry, 2022 Primary adrenal insufficiency rarely occurs due to infections, which consequently involves destruction or dysfunction of both adrenal cortices. Tuberculous adrenalitis is still a frequent cause of adrenal insufficiency in developing countries. We present
Pooja Govind +2 more
doaj +1 more source
The hepatoadrenal syndrome: A common yet unrecognized clinical condition [PDF]
, 2005 Objective: Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-
Acton +51 more
core +1 more source
Pituitary-adrenal axis in Prader Willi syndrome [PDF]
, 2016 Purpose: Prader Willi syndrome (PWS) is a rare genetic condition that has concurrent endocrinological insufficiencies. The presence of growth hormone deficiency has been well documented, but adrenal insufficiency (AI) is not widely reported. A review was
Edgar, Olivia S. +2 more
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Clinical Case Reports, 2022 AbstractPrimary adrenal insufficiency is a potentially life‐threatening condition. We report a case of a 49‐year‐old female patient who presented to the hospital for evaluation of dizziness, nausea, and vomiting. Darkening of the palmar creases and tongue was noted.
Mihail Zilbermint, Andrew P. Demidowich
openaire +3 more sources
Symptomatic adrenal insufficiency during inhaled corticosteroid treatment [PDF]
, 2001 Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment.
Clayton, P.E. +5 more
core +1 more source