Results 91 to 100 of about 4,267,390 (291)

The challenge to differentiate between sarcoma or adrenal carcinoma—an observational study

Rare Tumors, 2021
Background Adrenal sarcomas are rare malignant tumors with structural and clinical similarities to sarcomatoid adrenocortical carcinoma. Preoperative diagnosis of tumors of the adrenal gland can be challenging and often misleading thus detaining patients
Eva M Dobrindt, Wolfgang Saeger, Hendrik Bläker, Martina T Mogl, Marcus Bahra, Johann Pratschke, Nada Rayes   +6 more
doaj   +1 more source

“Non-Functional” Adrenal Tumors and the Risk of Incident Diabetes and Cardiovascular Outcomes: A Cohort Study

Annals of Internal Medicine, 2016
The use of cross-sectional abdominal imaging has increased the incidental detection of adrenal tumors (1, 2). Imaging and autopsy series estimate that the prevalence of adrenal tumors is 1% to 10% (35), with higher occurrences with older age (4, 5 ...
Diana Lopez, M. Luque-Fernández, Amy Steele, G. Adler, A. Turchin, Anand Vaidya   +5 more
semanticscholar   +1 more source

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto   +52 more
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Pathohistological Diagnosis of Adrenal Tumors: Experience of a Single Center

Southeastern European Medical Journal, 2020
Introduction: To investigate adrenal tumors of patients operated on at the University Hospital Center Osijek from 2016 to 2019 for the purpose of examining the location and histopathological findings of the tumors and determining whether there is a ...
Ivan Lekić, Veronika Banović, Ksenija Marjanović, Borna Kovačić, Ivan Feldi, Tatjana Bačun   +5 more
doaj   +1 more source

Testicular Adrenal Rest Tumors: Current Insights on Prevalence, Characteristics, Origin, and Treatment.

Endocrine reviews, 2019
This review provides the reader with current insights on testicular adrenal rest tumors (TARTs), a complication in male patients with congenital adrenal hyperplasia (CAH).
M. Engels, P. Span, A. V. van Herwaarden, F. Sweep, N. Stikkelbroeck, Hedi L. Claahsen-van der Grinten   +5 more
semanticscholar   +1 more source

Clinical case seminar - Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita [PDF]

, 2002
Mutations in the orphan nuclear receptor DAX-1 cause X-linked adrenal hypoplasia congenita. Affected boys usually present with primary adrenal failure in early infancy or childhood.
Beck-Peccoz, P, Achermann, JC, Romoli, R, Spada, A, Mantovani, G, Persani, L, Jameson, JL, Ozisik, G, Borretta, G   +8 more
core  

A case of adrenal cavernous hemangioma resected due to tumor growth accompanied by intratumoral hemorrhage

IJU Case Reports
Introduction We describe a case of an adrenal cavernous hemangioma that was surgically resected because of tumor growth and intratumoral hemorrhage.
Takayuki Ueda, Masato Yanagi, Takashi Kusakabe, Takeshi Shigihara, Mikio Shibasaki, Masato Nagasawa, Tsutomu Hamasaki, Yukihiro Kondo   +7 more
doaj   +1 more source

Classic congenital adrenal hyperplasia with unilateral functional adrenal cortical adenoma: case report

Gynecological Endocrinology
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders related to adrenal steroid biosynthesis, and mainly caused by mutations in the CYP21A2 gene encoding 21-hydroxylase. Adrenal tumors are common in CAH, but functional adrenal
Qin Yan, Huancheng Su, Xuan Jing, Sufen Li, Xujiao Ji, Zhiping Zhang, Yanni Wang, Xia Huang, Tingting Xue, Xueqing Wu, Xiangrong Cui   +10 more
doaj   +1 more source

Diagnostic Value of Urinary Steroid Profiling in the Evaluation of Adrenal Tumors

Hormones & cancer, 2015
Radiological examination may unexpectedly reveal an adrenal mass. Current algorithms for differentiating between benign and malignant lesions mainly rely on size and densitometry on unenhanced CT, which have limited specificity.
T. Kerkhofs, M. Kerstens, I. Kema, T. Willems, H. Haak   +4 more
semanticscholar   +1 more source