Results 1 to 10 of about 307,039 (247)

β-adrenergic receptor responsiveness in aging heart and clinical implications

open access: yesFrontiers in Physiology, 2014
Elderly healthy individuals have a reduced exercise tolerance and a decreased left ventricle inotropic reserve related to increased vascular afterload, arterial-ventricular load mismatching, physical deconditioning and impaired autonomic regulation (the ...
N. Ferrara   +8 more
semanticscholar   +3 more sources

Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]

open access: yesArchives of Razi Institute, 2022
The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar   +3 more
doaj   +1 more source

FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes

open access: yesCell Reports, 2021
Summary: The contribution of adipose-derived FGF21 to energy homeostasis is unclear. Here we show that browning of inguinal white adipose tissue (iWAT) by β-adrenergic agonists requires autocrine FGF21 signaling. Adipose-specific deletion of the FGF21 co-
Mohammad Abu-Odeh   +18 more
doaj   +1 more source

Fingerprinting heterocellular β-adrenoceptor functional expression in the brain using agonist activity profiles

open access: yesFrontiers in Molecular Biosciences, 2023
Noradrenergic projections from the brainstem locus coeruleus drive arousal, attentiveness, mood, and memory, but specific adrenoceptor (AR) function across the varied brain cell types has not been extensively characterized, especially with agonists. This
Rachel A. Matt   +5 more
doaj   +1 more source

The Cholinergic System, the Adrenergic System and the Neuropathology of Alzheimer’s Disease

open access: yesInternational Journal of Molecular Sciences, 2021
Neurodegenerative diseases are a major public health problem worldwide with a wide spectrum of symptoms and physiological effects. It has been long reported that the dysregulation of the cholinergic system and the adrenergic system are linked to the ...
R. Bekdash
semanticscholar   +1 more source

Ligands of Adrenergic Receptors: A Structural Point of View

open access: yesBiomolecules, 2021
Adrenergic receptors are G protein-coupled receptors for epinephrine and norepinephrine. They are targets of many drugs for various conditions, including treatment of hypertension, hypotension, and asthma.
Yiran Wu, Liting Zeng, Suwen Zhao
semanticscholar   +1 more source

Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone

open access: yesFrontiers in Cardiovascular Medicine, 2022
Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials.
Alexander Silva   +3 more
doaj   +1 more source

Neural regulation of ILC2s in allergic airway inflammation

open access: yesFrontiers in Allergy, 2023
The sympathetic nervous system (SNS) and parasympathetic nervous system (PNS) regulate the effector functions of group 2 innate lymphoid cells (ILC2s) through β2 adrenergic receptor (ADRB2) and nicotinic/muscarinic cholinergic receptor signaling ...
Christopher M. Thomas   +3 more
doaj   +1 more source

Interconnection between Adrenergic and Dopaminergic Systems in Feeding Behavior in Neonatal Chicks [PDF]

open access: yesArchives of Razi Institute, 2021
Central dopaminergic (DAergic) and adrenergic systems have a prominent role in appetite regulation; however, their interaction(s) have not been studied in neonatal layer chickens.Therefore, the current study aimed to determine the interaction of central ...
F Zanganeh   +3 more
doaj   +1 more source

Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac CaV1.2 calcium channel

open access: yesFrontiers in Physiology, 2023
The cardiac calcium channel CaV1.2 conducts L-type calcium currents that initiate excitation-contraction coupling and serves as a crucial mediator of β-adrenergic regulation of the heart.
Liam Hovey   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy