Results 111 to 120 of about 186,020 (321)

Spinal Antinociceptive Action of Amiloride and Its Interaction with Tizanidine in the Rat Formalin Test

open access: yesPain Research and Management, 2015
BACKGROUND: Amiloride has been reported to produce a wide variety of actions, thereby affecting several ionic channels and a multitude of receptors and enzymes.
Handong Ouyang   +5 more
doaj   +1 more source

Current and novel biomarkers in cardiogenic shock

open access: yesEuropean Journal of Heart Failure, EarlyView.
A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko   +5 more
wiley   +1 more source

Impact of hyperoxia and phenylephrine on cerebral oxygenation: An experimental clinical study

open access: yesActa Anaesthesiologica Scandinavica, Volume 67, Issue 1, Page 57-65, January 2023., 2023
Abstract Background Oxygen supply to the brain is of special importance during intracranial surgery because it may be compromised by intracranial pathology. A high arterial blood pressure (mean arterial pressure above 80 mmHg) and a high arterial oxygen tension (PaO2 above 12 kPa) is therefore often targeted in these patients, when for example ...
Sofie S. Pedersen   +8 more
wiley   +1 more source

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation

open access: yesiScience, 2018
Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation.
Erin L. Brown   +9 more
doaj  

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

open access: yesExploration, EarlyView.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang   +7 more
wiley   +1 more source

Toward staging differentiation for posttraumatic stress disorder treatment

open access: yesActa Psychiatrica Scandinavica, Volume 147, Issue 1, Page 65-80, January 2023., 2023
Abstract Objectives Several medical and psychiatric disorders have stage‐based treatment decision‐making methods. However, international treatment guidelines for posttraumatic stress disorder (PTSD) fail to give specific treatment recommendations based on chronicity or stage of the disorder.
Mirjam J. Nijdam   +2 more
wiley   +1 more source

Allobaculum plays a predominant role in the activation of brown fat tissue by diallyl trisulfide

open access: yesFood Frontiers, EarlyView.
Diallyl trisulfide activates brown adipose tissue and prevents obesity by promoting the relative abundance of Allobaculum in the gut of mice. Oral supplementation of Allobaculum stercoricanis, a primary species in Allobaculum, activates brown adipose tissue and prevents obesity.
Yanzhou Hu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy