Results 11 to 20 of about 303,653 (355)
The Cholinergic System, the Adrenergic System and the Neuropathology of Alzheimer’s Disease
International Journal of Molecular Sciences, 2021 Neurodegenerative diseases are a major public health problem worldwide with a wide spectrum of symptoms and physiological effects. It has been long reported that the dysregulation of the cholinergic system and the adrenergic system are linked to the ...
R. Bekdash
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Ligands of Adrenergic Receptors: A Structural Point of View
Biomolecules, 2021 Adrenergic receptors are G protein-coupled receptors for epinephrine and norepinephrine. They are targets of many drugs for various conditions, including treatment of hypertension, hypotension, and asthma.
Yiran Wu, Liting Zeng, Suwen Zhao
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Frontiers in Cardiovascular Medicine, 2022 Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials.
Alexander Silva +3 more
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Frontiers in Physiology, 2023 The cardiac calcium channel CaV1.2 conducts L-type calcium currents that initiate excitation-contraction coupling and serves as a crucial mediator of β-adrenergic regulation of the heart.
Liam Hovey +5 more
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The Autonomic Nervous System Pulls the Strings to Coordinate Circadian HSC Functions
Frontiers in Immunology, 2020 As for many other adult stem cells, the behavior of hematopoietic stem and progenitor cells (HSPCs) is subjected to circadian regulatory patterns. Multiple HSPC functions, such as proliferation, differentiation or trafficking exhibit time-dependent ...
Andrés García-García +3 more
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Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture
Frontiers in Endocrinology, 2023 The inhibitory effect of growth hormone (GH) on adipose tissue growth and the stimulatory effect of GH on lipolysis are well known, but the mechanisms underlying these effects are not completely understood.
Lidan Zhao, Honglin Jiang
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Neural regulation of ILC2s in allergic airway inflammation
Frontiers in Allergy, 2023 The sympathetic nervous system (SNS) and parasympathetic nervous system (PNS) regulate the effector functions of group 2 innate lymphoid cells (ILC2s) through β2 adrenergic receptor (ADRB2) and nicotinic/muscarinic cholinergic receptor signaling ...
Christopher M. Thomas +3 more
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Adrenergic regulation of immune cell function and inflammation
Seminars in Immunopathology, 2020 The sympathetic nervous system integrates the functions of multiple organ systems by regulating their autonomic physiological activities. The immune system is regulated both locally and systemically by the neurotransmitters epinephrine and norepinephrine
D. Sharma, J. D. Farrar
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Beta-Adrenergic Agonists [PDF]
Pharmaceuticals, 2010 Inhaled β2-adrenoceptor (β2-AR) agonists are considered essential bronchodilator drugs in the treatment of bronchial asthma, both as symptoms-relievers and, in combination with inhaled corticosteroids, as disease-controllers. In this article, we first review the basic mechanisms by which the β2-adrenergic system contributes to the control of airway ...
Giovanni Barisione +3 more
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Life, 2021 Cross-talk between opioid and adrenergic receptors is well-characterized and involves second messenger systems, the formation of receptor heterodimers, and the presence of extracellular allosteric binding regions for the complementary ligand; however ...
Robert Root-Bernstein, Beth Churchill
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