Results 191 to 200 of about 346,427 (358)

Progress in Molecular Imprinting—From Inhibition of Enzymatic Activity to Regulation of Cellular Pathways

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova   +2 more
wiley   +1 more source

Proteomic Profiling Informs Mechanisms of Esophageal Adenocarcinoma Inhibition by Cranberry Proanthocyanidins

open access: yesMolecular Nutrition &Food Research, EarlyView.
In this study we utilized proteomic profiling to investigate mechanisms linked to the cancer‐inhibitory effect of cranberry proanthocyanidins (CPACs) on reflux‐induced esophageal adenocarcinoma in a rat model. The results indicate that CPAC inhibits cancer through targeting multiple hallmarks of cancer known to be dysregulated in progression to ...
Yun Zhang   +7 more
wiley   +1 more source

Insights Into the Pathophysiology of Catecholamine-Refractory Shock: A Narrative Review. [PDF]

open access: yesCureus
Gonçalves A   +3 more
europepmc   +1 more source

β3‐Adrenoceptor Agonist Effects on the Urinary Bladder Beyond Detrusor Relaxation

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims β3‐Adrenoceptor agonists such as mirabegron or vibegron reach pharmacokinetic steady‐state within a few days. However, maximum improvements in symptoms of the overactive bladder syndrome are reached at time points later than 4 weeks, that is, detrusor smooth muscle relaxation cannot fully explain clinical effects.
Martin C. Michel   +2 more
wiley   +1 more source

The Clinical Significance of the Subtypes of Detrusor Overactivity: A Systematic Review

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Detrusor overactivity (DO) is the “occurrence of detrusor contraction(s) during filling cystometry” [7] and can be “phasic” or “terminal” [26]. The aim of this systematic review was to establish whether there is any clinical significance between the different subtypes of DO in terms of demographics, underlying pathophysiology ...
Manisha Teji   +2 more
wiley   +1 more source

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