Results 261 to 270 of about 468,250 (391)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Quantitative [¹⁸F]FDOPA PET/CT for the characterization of biochemical phenotypes in paraganglioma and pheochromocytoma. [PDF]

EJNMMI Rep
Dahlmann P, Onkes M, Kunte S, Auer MK, Disko U, Wang K, Lottspeich C, Stüfchen I, Schweizer JROL, Mansour N, Brendel M, Schmid-Tannwald C, Fischer A, Nölting S, Auernhammer CJ, Reincke M, Bidlingmaier M, Werner RA, Kroiss M, Völter F.   +19 more
europepmc   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, EarlyView.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity. [PDF]

Front Immunol
Muntjewerff EM, Josyula VS, Lehmair F, Christoffersson G.   +3 more
europepmc   +1 more source

Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation

, 1996
Fanelli, Francesca
openalex   +1 more source

Adrenergic neuronal connections between the bilateral supraoptic nuclei in the rat hypothalamus.

, 1991
Hiromi Tsushima, Mayumi Mori, Tomohiro Matsuda   +2 more
openalex   +1 more source

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

British Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim, Junhyuk Woo, Sungmin Pak, Joonho Paik, Gyu‐Sang Hong, Ji Hun Wi, Sanghee Lee, Cristina Fenollar‐Ferrer, Kyungreem Han, Young Kee Shin, Uhtaek Oh   +10 more
wiley   +1 more source

Cholinergic suppression of heart rate acceleration during intrinsic optogenetic activation of sympathetic cardiac neurons in perfused hearts. [PDF]

Am J Physiol Heart Circ Physiol
Russo R, Moreno A, Dwyer MK, Skancke M, Trachiotis G, Mendelowitz D, Kay MW.   +6 more
europepmc   +1 more source

The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis

, 2016
Cheryl Cero, Maria Razzoli, Ruijun Han, Bhavani S. Sahu, Jessica Patricelli, Zeng Guo, Nathan A. Zaidman, John J. Miles, Scott M. O’Grady, Alessandro Bartolomucci   +9 more
openalex   +1 more source

β-Adrenergic Receptor Blockade in Chronic Heart Failure

, 2000
M. Bristow
semanticscholar   +1 more source