Results 271 to 280 of about 346,600 (346)

DEGENERATION AND REGENERATION OF ADRENERGIC NERVES IN THE AUTOTRANSPLANTED KIDNEY

open access: bronze, 1969
John E. Norvell   +2 more
openalex   +1 more source

Effects of vatinoxan on gastrointestinal motility, sedation, and antinociception during and after long‐lasting detomidine infusion in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Sedation in horses is typically achieved using alpha‐2 adrenoceptor agonists, although their use is associated with multiple side effects. A peripheral alpha‐2 adrenoceptor antagonist, vatinoxan, can alleviate many of these. Objectives To evaluate the effects of vatinoxan infusion on gastrointestinal motility, sedation, and ...
Bartlomiej Obrochta   +7 more
wiley   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow   +2 more
wiley   +1 more source

Drug Interactions With Excessive Daytime Sleepiness Treatments. [PDF]

open access: yesJ Pharm Technol
Thomas SV   +3 more
europepmc   +1 more source

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

open access: yesThe FEBS Journal, EarlyView.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain   +2 more
wiley   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

open access: yesThe FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima   +11 more
wiley   +1 more source

Deletion of PPARα in mouse brown adipocytes increases their De Novo Lipogenesis. [PDF]

open access: yesMol Metab
Batrow PL   +15 more
europepmc   +1 more source

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