Results 271 to 280 of about 346,427 (358)

Effects of vatinoxan on gastrointestinal motility, sedation, and antinociception during and after long‐lasting detomidine infusion in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Sedation in horses is typically achieved using alpha‐2 adrenoceptor agonists, although their use is associated with multiple side effects. A peripheral alpha‐2 adrenoceptor antagonist, vatinoxan, can alleviate many of these. Objectives To evaluate the effects of vatinoxan infusion on gastrointestinal motility, sedation, and ...
Bartlomiej Obrochta   +7 more
wiley   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow   +2 more
wiley   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

open access: yesThe FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Role of TRPV1 in neuroendocrine regulation: a potential target against obesity? [PDF]

open access: yesFront Immunol
Wang J   +6 more
europepmc   +1 more source

Perirenal Fat in Disease Progression: From Inflammatory Mediator to Therapeutic Target

open access: yesInternational Journal of Urology, EarlyView.
ABSTRACT Perirenal fat (PRF), the adipose tissue that encases the kidneys, has long been considered a passive energy reservoir and mechanical buffer. However, emerging evidence has identified PRF as a biologically active visceral fat depot that secretes adipocytokines, inflammatory mediators, and other bioactive molecules, and thereby contributes to ...
Eiji Kashiwagi
wiley   +1 more source

Hyperhidrosis: don't sweat it

open access: yesInternal Medicine Journal, EarlyView.
Abstract Hyperhidrosis is an under‐reported and under‐treated condition that causes significant patient morbidity. Secondary causes require consideration, but the vast majority of cases are idiopathic. The condition is encountered by a range of clinicians, including neurologists, dermatologists and endocrinologists, and it pays to be familiar with the ...
Mitchell J. Lycett, Karl Ng
wiley   +1 more source

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