Results 271 to 280 of about 468,250 (391)

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

The neuro-immune axis in cancer: mechanisms of innervation-driven tumor progression and therapeutic opportunities. [PDF]

Front Immunol
Zhang L, Zhu D, Wang J, Guo J, Jiang M, Qi X, Zhang Z, Zheng Z.   +7 more
europepmc   +1 more source

Phosphodiesterase 4 and Phosphatase 2A Differentially Regulate cAMP/Protein Kinase A Signaling for Cardiac Myocyte Contraction under Stimulation of β1 Adrenergic Receptor

, 2008
Vania De Arcangelis, Dagoberto Soto, Yang Xiang   +2 more
openalex   +1 more source

Activation mechanism of the β2-adrenergic receptor

Proceedings of the National Academy of Sciences of the United States of America, 2011
R. Dror, Daniel H Arlow, P. Maragakis, Thomas J. Mildorf, Albert C. Pan, Huafeng Xu, D. Borhani, D. Shaw   +7 more
semanticscholar   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

Enhancing Caudal Analgesia in Children: A Narrative Review of Clonidine and Dexmedetomidine as Adjuvants. [PDF]

Cureus
Vaswani A, Bairwa K, Kewalramani R, Gangani J, Mohan V.   +4 more
europepmc   +1 more source

Norepinephrine Involvment in Penile Detumescence [PDF]

, 1990
Diederichs, W., Lue, Tom F., Stief, Christian Georg, Tanagho, Emil A.   +3 more
core   +1 more source

Long-term niacin treatment induces insulin resistance and adrenergic responsiveness in adipocytes by adaptive downregulation of phosphodiesterase 3B

, 2014
Mattijs M. Heemskerk, Sjoerd A.A. van den Berg, Amanda C. M. Pronk, Jan‐Bert van Klinken, Mariëtte R. Boon, Louis M. Havekes, Patrick C.N. Rensen, Ko Willems van Dijk, Vanessa van Harmelen   +8 more
openalex   +1 more source

Molecular Pathways: Beta-Adrenergic Signaling in Cancer

Clinical Cancer Research, 2011
Steven W. Cole, Anil K. Sood
semanticscholar   +1 more source

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto, Denis Lima Oliveira, José Britto‐Júnior, Alex Henrique Miller, Flaviano Lorenzon, Felipe Fernandes Jacintho, Valéria Barbosa de Souza, Fernanda Viviane Mariano, André Almeida Schenka, Fabiola Zakia Mónica, Adriano Fregonesi, Edson Antunes, Gilberto De Nucci   +12 more
wiley   +1 more source