Results 21 to 30 of about 186,020 (321)

Design and Implementation of Computeraided Learning Module in Pharmacology for Vasoactive Drugs: An Experience from a State Medical College in Haryana, India [PDF]

Journal of Clinical and Diagnostic Research
Introduction: In the Competency-based Medical Education (CBME) curriculum, one of the core competencies involves demonstrating the effects of autonomic drugs.
Jayant Kumar Kairi, Nitika Sharma
doaj   +1 more source

Effect of Nebulisation with Dexmedetomidine versus Magnesium Sulphate on Haemodynamic Response to Laryngoscopy and Intubation and Incidence of Postoperative Sore Throat: A Randomised Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Laryngoscopy and endotracheal intubation are essential procedures in general anaesthesia but can induce sympathetic hyperactivity, leading to transient increase in blood pressure and Heart Rate (HR).
Fateh Pal Singh Gill, Chhaya Suryawanshi
doaj   +1 more source

Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response

Frontiers in Immunology, 2018
An immune response must be tightly controlled so that it will be commensurate with the level of response needed to protect the organism without damaging normal tissue. The roles of cytokines and chemokines in orchestrating these processes are well known,
Guanxi Qiao, Minhui Chen, Mark J. Bucsek, Elizabeth A. Repasky, Bonnie L. Hylander   +4 more
doaj   +1 more source

Evaluation of sweating responses in patients with systemic connective tissue disorders using the quantitative sudomotor axon reflex test

Journal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 208-216, December 2022., 2022
We investigated 85 patients on the relationship between the axon reflex sweat volume or the reaction time and Raynaud's phenomenon, skin symptoms and patient background. Most patients did not show a decrease in sweating, but one in three patients showed less sweating in summer than in winter.
Miwa Ashida, Shimpei Morimoto, Mariko Yozaki, Daisuke Ehara, Yuta Koike, Hiroyuki Murota   +5 more
wiley   +1 more source

Synthesis, Docking Study and β-Adrenoceptor Activity of Some New Oxime Ether Derivatives

Molecules, 2014
A new series of oxime ethers 4a–z was designed and synthesized to test the blocking activity against β1 and β2-adrenergic receptors. Docking of these ether derivatives into the active site of the identified 3D structures of β1 and β2-adrenergic receptors
Hazem A. Ghabbour, Eman R. El-Bendary, Mahmoud B. El-Ashmawy, Mohamed M. El-Kerdawy   +3 more
doaj   +1 more source

β-Adrenergic Blockers [PDF]

The Journal of Clinical Hypertension, 2011
KEY POINTS AND PRACTICAL RECOMMENDATIONS: •  β-Blockers are appropriate treatment for patients with hypertension and those who have concomitant ischemic heart disease, heart failure, obstructive cardiomyopathy, or certain arrhythmias. •  β-Blockers can be used in combination with other antihypertensive drugs to achieve maximal blood pressure control ...
Elijah Saunders, William H. Frishman
openaire   +3 more sources

Adrenergic Modulation with Photochromic Ligands [PDF]

Angewandte Chemie International Edition, 2020
Adrenoceptors are ubiquitous and regulate heart and respiratory rate, digestion, metabolism, and vascular tone. They can be activated or blocked with adrenergic drugs, but systemic administration causes broad adverse effects. We have developed photochromic ligands (adrenoswitches) to switch on and off adrenoceptor activity on demand at selected ...
Davia Prischich, Alexandre M. J. Gomila, Santiago Milla‐Navarro, Gemma Sangüesa, Rebeca Diez‐Alarcia, Beatrice Preda, Carlo Matera, Montserrat Batlle, Laura Ramírez, Ernest Giralt, Jordi Hernando, Eduard Guasch, J. Javier Meana, Pedro de la Villa, Pau Gorostiza   +14 more
openaire   +7 more sources

Brown adipose tissue and regulation of human body weight

Diabetes/Metabolism Research and Reviews, Volume 39, Issue 1, January 2023., 2023
Abstract Background Approximately 30% of the global population is affected by obesity. Traditional non‐surgical measures for weight loss have limited efficacy and tolerability. Therefore, there is a need for novel, effective therapies. Brown adipose tissue (BAT) has been implicated in physiological energy expenditure, indicating that it could be ...
Elissa Harb, Omar Kheder, Gishani Poopalasingam, Razi Rashid, Akash Srinivasan, Chioma Izzi‐Engbeaya   +5 more
wiley   +1 more source

Single Cell Sequencing of the Pineal Gland: The Next Chapter

Frontiers in Endocrinology, 2019
The analysis of pineal cell biology has undergone remarkable development as techniques have become available which allow for sequencing of entire transcriptomes and, most recently, the sequencing of the transcriptome of individual cells.
Steven L. Coon, Cong Fu, Cong Fu, Steven W. Hartley, Lynne Holtzclaw, Joseph C. Mays, Michael C. Kelly, Matthew W. Kelley, James C. Mullikin, Martin F. Rath, Luis E. Savastano, David C. Klein   +11 more
doaj   +1 more source

Postnatal - Physiological Research of the Bronchial Receptor System Development on the Isolated Preparation of The Human Trachea In Vitro

Biomolecules & Biomedicine, 2006
Research was done on pharmacological-physiological development of the bronchial receptor system on the smooth muscles of trachea in the newborn children, alive-born and stillborn children.
Aziz Šukalo, Hilmi Islami, Ragib Shabani, Hilmi Dauti, Skender Kutllovci, Bashkim Kastrati   +5 more
doaj   +1 more source