Adrenergic Myocarditis in Pheochromocytoma [PDF]
The clinical presentation of pheochromocytoma is variable and many biochemical and imaging methods have been suggested to improve the diagnostic accuracy of what has been termed "the great masquerader". This case-report is of a middle-aged woman with a non-specific clinical presentation suggesting acute coronary syndrome or subacute myocarditis ...
Roghi, A+4 more
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Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics
Increased cardiac contractility during the fight-or-flight response is caused by β-adrenergic augmentation of CaV1.2 voltage-gated calcium channels1–4.
Guoxia Liu+16 more
semanticscholar +1 more source
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes
Summary: The contribution of adipose-derived FGF21 to energy homeostasis is unclear. Here we show that browning of inguinal white adipose tissue (iWAT) by β-adrenergic agonists requires autocrine FGF21 signaling. Adipose-specific deletion of the FGF21 co-
Mohammad Abu-Odeh+18 more
doaj
Introduction We sought to characterize the prevalence and factors characteristic of head and neck paragangliomas (HNPGLs) that secrete catecholamines to inform best practices for diagnosis and management.
Joshua D. Smith+3 more
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Design and Implementation of Computeraided Learning Module in Pharmacology for Vasoactive Drugs: An Experience from a State Medical College in Haryana, India [PDF]
Introduction: In the Competency-based Medical Education (CBME) curriculum, one of the core competencies involves demonstrating the effects of autonomic drugs.
Jayant Kumar Kairi, Nitika Sharma
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Effect of Nebulisation with Dexmedetomidine versus Magnesium Sulphate on Haemodynamic Response to Laryngoscopy and Intubation and Incidence of Postoperative Sore Throat: A Randomised Clinical Trial [PDF]
Introduction: Laryngoscopy and endotracheal intubation are essential procedures in general anaesthesia but can induce sympathetic hyperactivity, leading to transient increase in blood pressure and Heart Rate (HR).
Fateh Pal Singh Gill, Chhaya Suryawanshi
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Adrenergic Signaling: A Targetable Checkpoint Limiting Development of the Antitumor Immune Response
An immune response must be tightly controlled so that it will be commensurate with the level of response needed to protect the organism without damaging normal tissue. The roles of cytokines and chemokines in orchestrating these processes are well known,
Guanxi Qiao+4 more
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Synthesis, Docking Study and β-Adrenoceptor Activity of Some New Oxime Ether Derivatives
A new series of oxime ethers 4a–z was designed and synthesized to test the blocking activity against β1 and β2-adrenergic receptors. Docking of these ether derivatives into the active site of the identified 3D structures of β1 and β2-adrenergic receptors
Hazem A. Ghabbour+3 more
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KEY POINTS AND PRACTICAL RECOMMENDATIONS: • β-Blockers are appropriate treatment for patients with hypertension and those who have concomitant ischemic heart disease, heart failure, obstructive cardiomyopathy, or certain arrhythmias. • β-Blockers can be used in combination with other antihypertensive drugs to achieve maximal blood pressure control ...
Elijah Saunders, William H. Frishman
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Single Cell Sequencing of the Pineal Gland: The Next Chapter
The analysis of pineal cell biology has undergone remarkable development as techniques have become available which allow for sequencing of entire transcriptomes and, most recently, the sequencing of the transcriptome of individual cells.
Steven L. Coon+11 more
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