Results 41 to 50 of about 307,039 (247)
Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists
Nature Neuroscience, 2015 Do sedatives engage natural sleep pathways? It is usually assumed that anesthetic-induced sedation and loss of righting reflex (LORR) arise by influencing the same circuitry to lesser or greater extents.
Zhe Zhang +14 more
semanticscholar +1 more source
Transmural Autonomic Regulation of Cardiac Contractility at the Intact Heart Level
Frontiers in Physiology, 2019 The relationship between cardiac excitability and contractility depends on when Ca2+ influx occurs during the ventricular action potential (AP). In mammals, it is accepted that Ca2+ influx through the L-type Ca2+ channels occurs during AP phase 2 ...
Yuriana Aguilar-Sanchez +4 more
doaj +1 more source
β2-adrenergic receptor knockout mice exhibit A diabetic retinopathy phenotype. [PDF]
PLoS ONE, 2013 There is considerable evidence from our lab and others for a functional link between β-adrenergic receptor and insulin receptor signaling pathways in retina.
Youde Jiang +5 more
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Adipocyte, 2019 Ghrelin has garnered interest as a gut-derived regulator of lipid metabolism, beyond its classical roles in driving appetite and growth hormone release.
Daniel T. Cervone +3 more
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Cancer cells become less deformable and more invasive with activation of β-adrenergic signaling
Journal of Cell Science, 2016 Invasion by cancer cells is a crucial step in metastasis. An oversimplified view in the literature is that cancer cells become more deformable as they become more invasive.
Tae-Hyung Kim +8 more
semanticscholar +1 more source
Cardiac Effects of Attenuating Gsα - Dependent Signaling. [PDF]
PLoS ONE, 2016 Inhibition of β-adrenergic signalling plays a key role in treatment of heart failure. Gsα is essential for β-adrenergic signal transduction. In order to reduce side-effects of beta-adrenergic inhibition diminishing β-adrenergic signalling in the heart at
Marcus R Streit +9 more
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Aripiprazole induced priapism: A case report
Archives of Mental Health, 2015 Background: Priapism is a urologic emergency representing a true disorder of penile erection that persists beyond or is unrelated to sexual interest or stimulation. Variety of drugs is known to produce priapism, including psychotropics. Case description:
Satya K Trivedi +2 more
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Journal of Lipid Research, 1981 The aim of this study was to define the role of the alpha-adrenergic receptor in the regulation of lipolysis by human adipocytes. Glycerol production by isolated human adipocytes was stimulated by the pure beta-adrenergic agonist isoproterenol in a dose ...
E E Wright, E R Simpson
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Pregnancy modifies the α2-β-adrenergic receptor functional balance in rabbit fat cells
Journal of Lipid Research, 1999 The sympathetic nervous system controls lipolysis in fat by activation of four adrenergic receptors: β1, β2, β3, and α2. During pregnancy, maternal metabolism presents anabolic and catabolic phases, characterized by modifications of fat responsiveness to
Alain Bousquet-Mélou +4 more
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