Results 61 to 70 of about 186,020 (321)
Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang+8 more
wiley +1 more source
Isoprenaline increases Excursive Restitution Slope in the Conscious Rabbit with Ischaemic Heart Failure [PDF]
Background: An increased QT/RR slope is hypothesized to be predictive of sudden cardiac death after myocardial infarction. Previous studies have shown that beta-adrenergic stimulation increases QT/RR slope, but the effects of beta-adrenergic stimulation on QT/RR slope in heart failure are unknown.
arxiv
The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao+7 more
wiley +1 more source
Abstract Introduction The ability of ablative fractional lasers (AFL) to enhance topical drug uptake is well established. After AFL delivery, however, drug clearance by local vasculature is poorly understood. Modifications in vascular clearance may enhance AFL‐assisted drug concentrations and prolong drug dwell time in the skin.
Emily Wenande+8 more
wiley +1 more source
Dynamic re-wiring of protein interaction: The case of transactivation [PDF]
We are looking at local protein interaction networks from the perspective of directed, labeled graphs with quantitative values for monotonic changes in concentrations. These systems can be used to perform stability analysis for a stable attractor, given initial values.
arxiv
Exploring barriers to utilizing local agricultural products in the catering industry
Abstract Both the proportion and expenditure of dining out and takeaway in Taiwan have been increasing year by year. This study investigates the factors influencing the catering service providers (CSPs) procurement of domestically produced or imported food materials.
Wan‐Yu Liu+2 more
wiley +1 more source
How songs from growing up and viewers' attachment styles affect video ads' effectiveness
Abstract We propose that the positive effect of coming‐of‐age songs on ad effectiveness arises from a mediation process where the music‐evoked interpersonal memories of growing up stored in the brain and their accompanying emotions inevitably play a role, but not so straightforwardly as previously suggested.
Carlos J. S. Lourenço+5 more
wiley +1 more source
ABSTRACT Background Prior work has linked work stressors to asthma. However, research related to gender‐specific associations remains sparse and yielded mixed results. We aimed to address this gap. Methods We drew on cross‐sectional data from the 2015 National Health Interview Survey (individual‐level response rate = 79.7%).
Adrian Loerbroks+5 more
wiley +1 more source
Selectivity and Maximum Response of Vibegron and Mirabegron for β3-Adrenergic Receptors
: Background: The β3-adrenergic agonists vibegron and mirabegron have shown favorable safety profiles and efficacy for the treatment of overactive bladder.
Benjamin M. Brucker, MD+3 more
doaj
Buffering blood pressure fluctuations by respiratory sinus arrhythmia may in fact enhance them: a theoretical analysis [PDF]
Using a three-compartment model of blood pressure dynamics, we analyze theoretically the short term cardiovascular variability: how the respiratory-related blood pressure fluctuations are buffered by appropriate heart rate changes: i.e. the respiratory sinus arrhythmia.
arxiv