Results 61 to 70 of about 186,020 (321)

Hypothalamus Regulates Anabolic Metabolism of Articular Cartilage Superficial Chondrocytes through PGE2 Skeletal Interoception

open access: yesAdvanced Science, EarlyView.
Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang   +8 more
wiley   +1 more source

Isoprenaline increases Excursive Restitution Slope in the Conscious Rabbit with Ischaemic Heart Failure [PDF]

open access: yesarXiv, 2009
Background: An increased QT/RR slope is hypothesized to be predictive of sudden cardiac death after myocardial infarction. Previous studies have shown that beta-adrenergic stimulation increases QT/RR slope, but the effects of beta-adrenergic stimulation on QT/RR slope in heart failure are unknown.
arxiv  

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

open access: yesAdvanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao   +7 more
wiley   +1 more source

Local vasoregulative interventions impact drug concentrations in the skin after topical laser‐assisted delivery

open access: yesLasers in Surgery and Medicine, Volume 54, Issue 10, Page 1288-1297, December 2022., 2022
Abstract Introduction The ability of ablative fractional lasers (AFL) to enhance topical drug uptake is well established. After AFL delivery, however, drug clearance by local vasculature is poorly understood. Modifications in vascular clearance may enhance AFL‐assisted drug concentrations and prolong drug dwell time in the skin.
Emily Wenande   +8 more
wiley   +1 more source

Dynamic re-wiring of protein interaction: The case of transactivation [PDF]

open access: yesarXiv, 2006
We are looking at local protein interaction networks from the perspective of directed, labeled graphs with quantitative values for monotonic changes in concentrations. These systems can be used to perform stability analysis for a stable attractor, given initial values.
arxiv  

Exploring barriers to utilizing local agricultural products in the catering industry

open access: yesAgribusiness, EarlyView.
Abstract Both the proportion and expenditure of dining out and takeaway in Taiwan have been increasing year by year. This study investigates the factors influencing the catering service providers (CSPs) procurement of domestically produced or imported food materials.
Wan‐Yu Liu   +2 more
wiley   +1 more source

How songs from growing up and viewers' attachment styles affect video ads' effectiveness

open access: yesPsychology &Marketing, Volume 40, Issue 1, Page 209-233, January 2023., 2023
Abstract We propose that the positive effect of coming‐of‐age songs on ad effectiveness arises from a mediation process where the music‐evoked interpersonal memories of growing up stored in the brain and their accompanying emotions inevitably play a role, but not so straightforwardly as previously suggested.
Carlos J. S. Lourenço   +5 more
wiley   +1 more source

Work Stressors and Asthma in Female and Male US Workers: Findings From the National Health Interview Survey

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Prior work has linked work stressors to asthma. However, research related to gender‐specific associations remains sparse and yielded mixed results. We aimed to address this gap. Methods We drew on cross‐sectional data from the 2015 National Health Interview Survey (individual‐level response rate = 79.7%).
Adrian Loerbroks   +5 more
wiley   +1 more source

Selectivity and Maximum Response of Vibegron and Mirabegron for β3-Adrenergic Receptors

open access: yesCurrent Therapeutic Research, 2022
: Background: The β3-adrenergic agonists vibegron and mirabegron have shown favorable safety profiles and efficacy for the treatment of overactive bladder.
Benjamin M. Brucker, MD   +3 more
doaj  

Buffering blood pressure fluctuations by respiratory sinus arrhythmia may in fact enhance them: a theoretical analysis [PDF]

open access: yesarXiv, 2010
Using a three-compartment model of blood pressure dynamics, we analyze theoretically the short term cardiovascular variability: how the respiratory-related blood pressure fluctuations are buffered by appropriate heart rate changes: i.e. the respiratory sinus arrhythmia.
arxiv  

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