Results 81 to 90 of about 444,528 (410)
Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]
Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Cardiac Effects of Attenuating Gsα - Dependent Signaling. [PDF]
Inhibition of β-adrenergic signalling plays a key role in treatment of heart failure. Gsα is essential for β-adrenergic signal transduction. In order to reduce side-effects of beta-adrenergic inhibition diminishing β-adrenergic signalling in the heart at
Marcus R Streit+9 more
doaj +1 more source
Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. [PDF]
Rosacea is a chronic inflammatory disease with transient and non-transient redness as key characteristics. Brimonidine is a selective α2-adrenergic receptor (AR) agonist approved for persistent facial erythema of rosacea based on significant efficacy and
Detmar, Michael+6 more
core +2 more sources
ABSTRACT Objective Music interventions have been shown to have beneficial effects on hemodynamic parameters, pain, and anxiety in various medical settings. However, music interventions in the setting of acute stroke have not been studied. The objective of this trial was to perform a pilot feasibility study of music interventions in the setting of acute
Jeffrey J. Fletcher+7 more
wiley +1 more source
Rotator cuff tears, a common musculotendinous injury, often lead to permanent functional disability. A novel hyaluronic acid‐based hydrogel shows promise in promoting muscle regeneration after rotator cuff repair. The hydrogel reduces fibrosis, fatty infiltration, and muscle atrophy while supporting vascularization in a murine model.
Morgan R. Pfaff+11 more
wiley +1 more source
Ghrelin has garnered interest as a gut-derived regulator of lipid metabolism, beyond its classical roles in driving appetite and growth hormone release.
Daniel T. Cervone+3 more
doaj +1 more source
The β2-adrenergic receptor has been shown to be involved in neuroendocrine differentiation and to contribute to the development of aggressive prostate cancer.
Ilaria Guerriero+5 more
doaj +1 more source
A shrinkage‐resistant hydrogel is developed to confer post‐fabrication shape fidelity. The hydrogel, based on recombinant spider silk protein eADF4(C16)‐RGD and collagen‐I, exhibits tunable mechanical properties and shrink‐resistance in the presence of fibroblasts as well as muscle cells.
Xuen J. Ng+10 more
wiley +1 more source