Results 101 to 110 of about 989,789 (251)

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Effect of adrenergic antagonists on epinephrine-induced uptake of I-PGUS across the BBB.

open access: yes, 2015
Upper panel shows that more general alpha, alpha1, and alpha2 antagonists but not beta antagonists blocked epinephrine’s effect. Lower panel shows results that the highly selective alpha1 adrenergic receptor antagonist benoxathian but not the highly ...
William S. Sly (358930)   +5 more
core   +1 more source

The Musculoskeletal Consequences of Mouth Breathing in Adults: A Systematic Review

open access: yesThe Laryngoscope, EarlyView.
Chronic mouth breathing can have a negative impact on posture, cause temporomandibular joint dysfunction (TMD), reduced masticatory muscle activity and efficiency, and suprahyoid muscle overuse. Postural changes include a head forward posture and increased lumbar lordosis.
Raewyn G. Campbell   +13 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Alpha-adrenergic antagonists and iris dynamics: Challenges and solutions in cataract surgery

open access: yesBMC Ophthalmology
Background Alpha-1 adrenergic receptor antagonists (α1-ARAs) are frequently used in treatment of Hypertension and symptomatic benign prostatic hypertrophy (BPH).
Jaya Kaushik   +5 more
doaj   +1 more source

Alpha-Blocker Prescribing Trends for Ureteral Stones: A Single-Centre Study

open access: yesResearch and Reports in Urology, 2022
Liang G Qu,1,2,* Garson Chan,1– 3,* Johan Gani1,2,4 1Department of Urology, Austin Health, Heidelberg, Victoria, Australia; 2Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia; 3Department of Surgery, Division of ...
Qu LG, Chan G, Gani J
doaj  

Vasopressin increases blood glucose in pygmy goats (Capra hircus) by an alpha-adrenergic mechanism.

open access: yes, 1991
1. Twelve adult pygmy goats were used to investigate the mechanism of vasopressin (VP) induced hyperglycaemia. 2. VP (0.4 microgram/kg or 0.75 microgram/kg body weight) injected i.p. produced a long lasting hyperglycaemia. 3.
Scharrer E, Rossi R
core   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers   +5 more
wiley   +1 more source

Adrenergic regulation of the skeletal alpha-actin gene promoter during myocardial cell hypertrophy

open access: yes, 1991
The skeletal alpha-actin gene is expressed in fetal rat heart and is induced during norepinephrine (NE)-stimulated hypertrophy in cultures of neonatal rat cardiac myocytes.
Kedes, L, Bishopric, N H
core   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

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