Results 231 to 240 of about 37,264 (269)

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

open access: yesTraffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby   +3 more
wiley   +1 more source

Tryptophan metabolites clearance in hemodialyzed patients. [PDF]

open access: yesAmino Acids
Zakrocka I   +8 more
europepmc   +1 more source

Optimized SPE‐HPLC‐FLD Method for the Simultaneous Determination of Olaparib, Propranolol, and Furosemide in Human Urine

open access: yesBiomedical Chromatography, Volume 40, Issue 8, August 2026.
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris   +2 more
wiley   +1 more source

Effect of Antihypertensive Drug Classes on Stroke Prevention: A Systematic Review and Meta-Analysis. [PDF]

open access: yesCureus
Shams Z   +8 more
europepmc   +1 more source

Differential Impact of Pharmacokinetic and Pharmacodynamic Variability on Response to Combination Therapy

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Interindividual variability (IIV) in drug response complicates both fixed‐dose design and individualized therapy. Understanding how pharmacokinetic (PK) and pharmacodynamic (PD) processes jointly shape this variability is essential, particularly in combination therapy, where multiple interacting pathways influence outcomes. This study employed
Kuteesa R. Bisaso   +3 more
wiley   +1 more source

Beta adrenergic signaling as a therapeutic target for autoimmunity. [PDF]

open access: yesJ Neuroimmunol
Lauten TH   +6 more
europepmc   +1 more source

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