Results 21 to 30 of about 900,428 (163)

"In vitro" study of the mode of action of antidepressants in cell culture models : comparison of the effects of "Hypericum perforatum L." extracts and classical synthetic compounds on the [beta]-adrenergic signal pathway [PDF]

open access: yes, 2005
The clinical effectiveness of the plant extract of Hypericum perforatum L. in treating mild to moderate depression is well established. The extract shows a more favourable side effect profile than other antidepressant drugs, like tricyclics and selective
Wirz, Adrian
core   +1 more source

Cognitive Function and Urologic Medications for Lower Urinary Tract Symptoms [PDF]

open access: yesInternational Neurourology Journal, 2020
Special considerations should be made when selecting medications for the treatment of lower urinary tract symptoms (LUTS) in older patients especially those over 65 years old.
Yeon Joo Kim, Bum Sik Tae, Jae Hyun Bae
doaj   +1 more source

Preponderance of alpha 2- over beta 1-adrenergic receptor sites in human fat cells is not predictive of the lipolytic effect of physiological catecholamines

open access: yesJournal of Lipid Research, 1983
Adrenergic control of human fat cell lipolysis is mediated by two kinds of receptor sites that are simultaneously stimulated by physiological amines. To establish a correlation between the binding characteristics of the receptor and biological functions,
M Lafontan, M Berlan, A Villeneuve
doaj   +1 more source

ENDOGENOUS BETA-ADRENERGIC RECEPTOR ANTAGONISTS (EBARA) IN HEALTH AND DISEASE [PDF]

open access: yes, 2017
Data accumulated in investigations under in vivo and in vitro conditions confirm author's concept about the existence of EBARA, certain endogenous biologically active substances in a healthy and pathologically altered organism when no betaadrenergic ...
Temnyalov, N.
core   +1 more source

Beta Adrenergic Signaling: A Targetable Regulator of Angiosarcoma and Hemangiosarcoma

open access: yesVeterinary Sciences, 2015
Human angiosarcomas and canine hemangiosarcomas are highly aggressive cancers thought to arise from cells of vascular origin. The pathological features, morphological organization, and clinical behavior of canine hemangiosarcomas are virtually ...
Erin B. Dickerson, Brad A. Bryan
doaj   +1 more source

Cardioprotective role of carvedilol in patients on chemotherapy: systematic review and meta-analysis of randomized clinical trials

open access: yesHorizonte Médico, 2018
Objective: Cancer therapy may cause cardiovascular toxicity even after successful treatment. It is unknown the cardioprotective role of carvedilol in this setting.
Lucía Florio Legnani   +2 more
doaj   +1 more source

Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines

open access: yesBMC Cancer, 2004
Background Previous research has indicated that at various organ sites there is a subset of adenocarcinomas that is regulated by beta-adrenergic and arachidonic acid-mediated signal transduction pathways.
Cakir Yavuz   +3 more
doaj   +1 more source

Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]

open access: yes, 1993
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J.   +5 more
core   +1 more source

Candesartan and carvedilol for primary prevention of subclinical cardiotoxicity in breast cancer patients without a cardiovascular risk treated with doxorubicin

open access: yesCancer Medicine, 2021
Background There is no proven primary preventive strategy for doxorubicin‐induced subclinical cardiotoxicity (DISC), especially among patients without a cardiovascular (CV) risk.
Myunhee Lee   +6 more
doaj   +1 more source

The role of plasma concentrations and drug characteristics of beta‐blockers in fall risk of older persons

open access: yesPharmacology Research & Perspectives, 2023
Beta‐blocker usage is inconsistently associated with increased fall risk in the literature. However, due to age‐related changes and interindividual heterogeneity in pharmacokinetics and dynamics, it is difficult to predict which older adults are more at ...
K. J. Ploegmakers   +11 more
doaj   +1 more source

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