Results 71 to 80 of about 136,170 (301)

Neutrophil stunning by metoprolol reduces infarct size

Nature Communications, 2017
Metoprolol is a selective β1 adrenergic receptor blocker that reduces cardiac infarct size and improves cardiac function. The drug is believed to act on cardiomyocytes; however, here the authors show that metoprolol exerts its beneficial effect on ...
Jaime García-Prieto, Rocío Villena-Gutiérrez, Mónica Gómez, Esther Bernardo, Andrés Pun-García, Inés García-Lunar, Georgiana Crainiciuc, Rodrigo Fernández-Jiménez, Vinatha Sreeramkumar, Rafael Bourio-Martínez, José M García-Ruiz, Alfonso Serrano del Valle, David Sanz-Rosa, Gonzalo Pizarro, Antonio Fernández-Ortiz, Andrés Hidalgo, Valentín Fuster, Borja Ibanez   +17 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Exploration of neural mechanisms underlying antidepressant-like property of Ziziphora clinopodioides Lam. essential oil using mouse forced swimming test: Involvement of the monoaminergic systems

Current Research in Physiology
Objective: Ziziphora clinopodioides has been valued in Iranian traditional medicine for various medicinal applications. This novel study was conducted to assess the antidepressant-like effect of the essential oil of Ziziphora clinopodioides (EOZC) and to
Saeedeh Ghaffarzadeh Shirabad, Samad Alimohammadi   +1 more
doaj   +1 more source

Fred A. Blocker with Bully

, 1940
This is a black and white photograph of Fred A. Blocker with Bully. Here, Bully is the live school mascot, and he is an English Bulldog. Bully and Blocker are seated on a platform outside a relatively large, enclosed dog house structure.
Blocker, Fred A.
core  

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Fred A. Blocker Entering Lee Hall

, 1940
This is a black and white photo of Fred A. Blocker in the doorway of Lee Hall on Mississippi State University campus. Blocker is propping the door open with his arm, and it is slightly ajar on the left side.https://scholarsjunction.msstate.edu/ua-blocker-
Blocker, Fred A.
core  

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Fred A. Blocker Seated on Stair Rail

, 1940
This is a black and white photo of Fred A. Blocker seated on a stair rail outside Lee Hall on Mississippi State University campus. Blocker is seated next to a lamppost on the stair rail. Stairs can be seen in the foreground, and more of Mississippi State
Blocker, Fred A.
core  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Treatment Patterns in Alpha-Blocker Therapy for Benign Prostatic Hyperplasia

American Journal of Men's Health, 2014
This study examined treatment patterns and patient characteristics of men initiating alpha adrenergic blocker therapy (alpha-blocker) for benign prostatic hyperplasia (BPH).
Michael J. Schoenfeld MA, Emily F. Shortridge PhD, Steven C. Gelwicks MS, Zhanglin Cui PhD, David G. Wong MD   +4 more
doaj   +1 more source