Results 241 to 250 of about 2,589,815 (356)

BETA ADRENERGIC RECEPTOR (BAR) BINDING CHARACTERISTICS AND ADENYLATE CYCLASE (AC) ACTIVITY IN THE PULMONARY ARTERY (PA) AND THORACIC AORTA (AO) [PDF]

, 1987
Philip W. Shaul, K H Muntz, L. Maximilian Buja   +2 more
openalex   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Cetacean loss of the master adipose tissue regulator β₃-adrenergic receptor may underlie their thick blubber and an Oligocene radiation and dispersal. [PDF]

Nat Commun
Tian R, Zhang T, Dong H, Seim I, Yang G.
europepmc   +1 more source

Intracellular Ca2+ and protein kinase C interact to regulate α1-adrenergic- and bradykinin receptor-stimulated phospholipase A2 activation in Madin-Darby canine kidney cells.

, 1991
Barbara Weiß, Paul A. Insel
openalex   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source

Chromogranin A deficiency attenuates tauopathy by altering epinephrine-alpha-adrenergic receptor signaling in PS19 mice. [PDF]

Nat Commun
Jati S, Munoz-Mayorga D, Shahabi S, Tang K, Tao Y, Dickson DW, Litvan I, Ghosh G, Mahata SK, Chen X.   +9 more
europepmc   +1 more source

β-Adrenergic Receptor Mediation of Stress-Induced Reinstatement of Extinguished Cocaine-Induced Conditioned Place Preference in Mice: Roles for β1 and β2 Adrenergic Receptors

Journal of Pharmacology and Experimental Therapeutics, 2012
O. Vranjkovic, Shona Hang, D. Baker, John R Mantsch   +3 more
semanticscholar   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Enhanced Sampling and Tailored Collective Variables Yield Reproducible Free Energy Landscapes of Beta-1 Adrenergic Receptor Activation. [PDF]

J Chem Theory Comput
Aureli S, Rizzi V, Piasentin N, Gervasio FL.   +3 more
europepmc   +1 more source

Inhibition of Na ⁺ -H ⁺ Exchange Prevents Hypertrophy, Fibrosis, and Heart Failure in β ₁ -Adrenergic Receptor Transgenic Mice [PDF]

, 2002
Stefan Engelhardt, Lutz Hein, U Keller, Kerstin Klämbt, Martin J. Lohse   +4 more
openalex   +1 more source