Results 241 to 250 of about 2,542,862 (407)
Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley +1 more source
Identification of the Cardiac Beta-Adrenergic Receptor Protein: Solubilization and Purification by Affinity Chromatography [PDF]
Robert J. Lefkowitz+2 more
openalex +1 more source
MAPT accumulation inhibited CHMP4B expression and thus disrupted ESCRT‐III‐mediated autophagosome‐lysosome fusion, which induced a vicious cycle between MAPT aggregation and autophagic deficits. Aerobic exercise could effectively block the vicious cycle and reverse autophagic deficits by promoting the β2‐AR‐RXRα‐CHMP4B‐ESCRT‐III pathway, reducing ...
Shu‐Guang Bi+12 more
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Implication of Central β<sub>2</sub> Adrenergic Receptor for the Development of Novel Drugs Against Alzheimer's Disease. [PDF]
Wang A+3 more
europepmc +1 more source
Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi+4 more
wiley +1 more source
Modulation of neuronal α1-adrenergic receptor reduces tauopathy and neuroinflammation by inhibiting the STING/NF-κB/NLRP3 signaling pathway in Alzheimer's disease mice. [PDF]
Li B+6 more
europepmc +1 more source
Activation mechanism of the β2-adrenergic receptor
R. Dror+7 more
semanticscholar +1 more source
Abstract Objectives To evaluate the risk of priapism in patients undergoing Dynamic—Penile duplex ultrasound (D‐PDU) who were referred to our Unit between January 2022 and December 2023. Patients and methods We enrolled 292 patients, of whom 268 underwent Dynamic—Penile duplex ultrasound for erectile dysfunction and 24 for Peyronie's disease.
Giuseppe Grande+6 more
wiley +1 more source