Results 271 to 280 of about 2,589,815 (356)

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

FAM20A Deficiency Drives Transcriptomic Dysregulation and Functional Impairment in Gingival Fibroblasts

open access: yesCell Proliferation, EarlyView.
FAM20A variants cause AI1G, marked by enamel defects, gingival overgrowth and ectopic calcifications. RNA sequencing of patient‐derived gingival fibroblasts showed dysregulated genes in adhesion, proliferation and signalling pathways. Functional assays revealed increased cell proliferation, impaired ECM interactions and osteogenesis, suggesting FAM20A ...
Kanokwan Sriwattanapong   +9 more
wiley   +1 more source

Sex difference of hepatic β-adrenergic receptor-function in rats

open access: diamond, 1990
Tatsurou Yagami   +2 more
openalex   +1 more source

Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

open access: yesNature, 2011
K. Chung   +9 more
semanticscholar   +1 more source

Ablation of Sympathetic Nerve-β3 Adrenergic Receptor-mediated Adipose Tissue Lipolysis Attenuates Alcohol-induced Liver Injury in Mice. [PDF]

open access: yesCell Mol Gastroenterol Hepatol
Wickramasinghe PB   +8 more
europepmc   +1 more source

A systematic review of glucocorticoid use in type 1 diabetes: Glycaemic effects and clinical management strategies

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Glucocorticoids (GCs) are widely utilised for the treatment of inflammatory and autoimmune conditions but often precipitate significant hyperglycaemia. People with type 1 diabetes (PWT1D) may be particularly affected due to the challenges of adjusting insulin dosing, for which recommendations remain unclear.
Alexandra Katz   +8 more
wiley   +1 more source

Photo-clenbuterol: Optical Control of β<sub>2</sub>-Adrenergic Receptor Signaling by Photoswitchable Ligand Efficacy. [PDF]

open access: yesJ Med Chem
Cao Y   +8 more
europepmc   +1 more source

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