Results 281 to 290 of about 2,542,862 (407)

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

The β₂-adrenergic receptor (<i>Adrb2</i>) entrains circadian gene oscillation and CD8⁺ T cell differentiation in response to virus infection. [PDF]

Sci Adv
Sharma D, Kohlbach KA, Maples R, Farrar JD.   +3 more
europepmc   +1 more source

Desensitization of beta-adrenergic receptors by beta-adrenergic agonists in a cell-free system: resensitization by guanosine 5'-(beta, gamma-imino)triphosphate and other purine nucleotides.

, 1976
Chhabirani Mukherjee, Robert J. Lefkowitz   +1 more
openalex   +1 more source

FAM20A Deficiency Drives Transcriptomic Dysregulation and Functional Impairment in Gingival Fibroblasts

Cell Proliferation, EarlyView.
FAM20A variants cause AI1G, marked by enamel defects, gingival overgrowth and ectopic calcifications. RNA sequencing of patient‐derived gingival fibroblasts showed dysregulated genes in adhesion, proliferation and signalling pathways. Functional assays revealed increased cell proliferation, impaired ECM interactions and osteogenesis, suggesting FAM20A ...
Kanokwan Sriwattanapong, Sermporn Thaweesapphithak, Chompak Khamwachirapitak, Pannagorn Sae‐ear, Sasiprapa Prommanee, Noppadol Sa‐Ard‐Iam, Suphalak Phothichailert, Han Sung Jung, Vorasuk Shotelersuk, Thantrira Porntaveetus   +9 more
wiley   +1 more source

Adrenal epinephrine facilitates erythropoietin gene activation by hypoxia through β2 adrenergic receptor interaction with Hif-2α. [PDF]

Am J Physiol Regul Integr Comp Physiol
Su X, Hildreth M, Rapaka S, Peng YJ, Nanduri J, Prabhakar NR.   +5 more
europepmc   +1 more source

β-Adrenergic Receptor Blockade in Chronic Heart Failure

, 2000
M. Bristow
semanticscholar   +1 more source

Emergence of Medetomidine in the Unregulated Drug Supply and Its Association With Hallucinogenic Effects

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction The unregulated drug supply in the United States is rapidly evolving, and veterinary tranquillisers have emerged as adulterants of concern, especially in illicitly‐manufactured fentanyl. Following the proliferation of xylazine, medetomidine, a more potent sedative, has recently appeared in multiple US states.
Adams L. Sibley, Madigan L. Bedard, Samuel Tobias, Brooke A. Chidgey, Irina G. Phillips, Alice Bell, Nabarun Dasgupta   +6 more
wiley   +1 more source

Prostate cancer incidence and mortality in men exposed to α1-adrenergic receptor antagonists. [PDF]

J Natl Cancer Inst
Björnebo L, Björnebo L, Razdan S, Discacciati A, Palsdottir T, Aly M, Nordström T, Eklund M, Lundon D, Grönberg H, Tewari A, Wiklund P, Kyprianou N, Lantz A.   +13 more
europepmc   +1 more source

Thyroid Hormone Regulation of Alpha-Adrenergic Receptors

, 1979
R. Sanders Williams, Robert J. Lefkowitz
openalex   +1 more source

Association of allergen stability and epithelial barrier function in sensitized patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Panallergen families differ in their stability to heat and pH, which affects both the severity and clinical manifestations of allergic reactions. The extent of epithelial barrier dysfunction is thought to influence sensitization to different allergens.
Hannes Nösslinger, Ewald Mair, Gertie Janneke Oostingh, Verena Ahlgrimm‐Siess, Anna Ringauf, Roland Lang   +5 more
wiley   +1 more source