Results 1 to 10 of about 4,983 (96)
PLoS ONE, 2022 Dopaminergic neuron degeneration in the midbrain plays a pivotal role in motor symptoms associated with Parkinson’s disease. However, non-motor symptoms of Parkinson’s disease and post-mortem histopathology confirm dysfunction in other brain areas ...
Predrag Jovanovic +7 more
doaj +2 more sources
Frontiers in Medicine, 2022 BackgroundThe optimal management of hypotensive patients during norepinephrine weaning is unclear. The primary study aim was to assess the ability of preload dependence to predict hypotension following norepinephrine weaning.
Stefan Andrei +8 more
doaj +1 more source
Norepinephrine use in cardiogenic shock patients is associated with increased 30 day mortality
ESC Heart Failure, 2022 Aims Norepinephrine is recommended as a first‐line vasopressor agent in the haemodynamic stabilization of cardiogenic shock. The survival benefit of norepinephrine therapy has not been demonstrated in clinical practice, however.
Xin Lu +8 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Purpose: The relative potency of norepinephrine and phenylephrine given as boluses to treat hypotension during spinal anesthesia for cesarean delivery has been reported but few data are available for infusions.
Jing Qian +13 more
doaj +1 more source
Dose-related effects of norepinephrine on early-stage endotoxemic shock in a swine model
Journal of Intensive Medicine, 2023 Background: The benefits of early use of norepinephrine in endotoxemic shock remain unknown. We aimed to elucidate the effects of different doses of norepinephrine in early-stage endotoxemic shock using a clinically relevant large animal model.
Hui Xiang +7 more
doaj +1 more source
BMC Anesthesiology, 2020 Background Data on the best norepinephrine bolus dose for management of hypotension are limited. The aim of this study was to compare the efficacy and safety of two norepinephrine bolus doses in the rescue management of maternal hypotension during ...
Yasmin S. Hassabelnaby +11 more
doaj +1 more source
Mobilisation of critically ill patients receiving norepinephrine: a retrospective cohort study
Critical Care, 2022 Background Mobilisation and exercise intervention in general are safe and feasible in critically ill patients. For patients requiring catecholamines, however, doses of norepinephrine safe for mobilisation in the intensive care unit (ICU) are not defined.
Maximilian Lindholz +12 more
doaj +1 more source
Inadvertent Extravasations of Norepinephrine
Clinical Case Reports, 2022 A 63-year-old male patient of diabetic ketoacidosis and septic shock was started on norepinephrine infusion following which he developed bulla and subcutaneous tissue ischemia in the event of inadvertent extravasations of norepinephrine. The patient improved after management with mechanical debridement of necrosed tissue and regular dressing of the ...
openaire +3 more sources
A cautionary note for researchers treating mice with the neurotransmitter norepinephrine
Biochemistry and Biophysics Reports, 2018 The sympathetic nervous system plays a crucial role in metabolic function and glucose homeostasis. Norepinephrine is the main neurotransmitter released from sympathetic neurons. The major goal of our studies was to examine the impact of norepinephrine on
Vance B. Matthews +2 more
doaj +1 more source
Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]
BMC Musculoskeletal Disorders, 2002 Background Fibromyalgia syndrome displays sympathetically maintained pain features such as frequent post-traumatic onset and stimuli-independent pain accompanied by allodynia and paresthesias.
Casanova Jose-Miguel +5 more
doaj +1 more source