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Structure of β-Adrenergic Receptors
2013β-Adrenergic receptors (βARs) control key physiological functions by transducing signals encoded in catecholamine hormones and neurotransmitters to activate intracellular signaling pathways. As members of the large family of G protein-coupled receptors (GPCRs), βARs have a seven-transmembrane helix topology and signal via G protein- and arrestin ...
Brueckner Florian +5 more
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Herz, 2002
The beta-adrenergic receptors of the myocardium play an important role in the regulation of heart function. The beta-adrenergic receptors belong to the family of G-protein coupled receptors. Three subtypes have been distinguished (beta1-, beta2-, and beta3-adrenoceptors).
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The beta-adrenergic receptors of the myocardium play an important role in the regulation of heart function. The beta-adrenergic receptors belong to the family of G-protein coupled receptors. Three subtypes have been distinguished (beta1-, beta2-, and beta3-adrenoceptors).
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Adrenergic Receptors and Kinins
1968Epinephrine, as it is known, exhibits a diphasic effect on the blood pressure. In hypertensive patients, if small amounts of epinephrine are used, the hypotension is more evident than hypertension (Greppi 1932, Goldenberger et al. 1948). The effect of nor-adrenaline is simply monophasic.
Federigo Sicuteri +4 more
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2014
β-Adrenergic receptors (β-ARs) have a key position not in to the overall regulation of cardiac function and have been shown to play an important role in various cardiac diseases and heart failure in particular. Beta adrenergic receptors (β-ARs) belong to the G protein-coupled receptor (GPCR) superfamily with widespread expression and cardiovascular ...
Konstantinos Makaritsis +1 more
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β-Adrenergic receptors (β-ARs) have a key position not in to the overall regulation of cardiac function and have been shown to play an important role in various cardiac diseases and heart failure in particular. Beta adrenergic receptors (β-ARs) belong to the G protein-coupled receptor (GPCR) superfamily with widespread expression and cardiovascular ...
Konstantinos Makaritsis +1 more
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Adrenergic receptors in the veins of the dog
European Journal of Pharmacology, 1969Abstract The actions of catecholamines and adrenergic blocking drugs on the veins of the dog (posterior vena cava, portal vein, femoral vein, lateral saphenous vein) were studied in vitro . In these experiments quantitative and qualitative differences were found. Superficial veins were more sensitive.
Serafim Guimarães, Walter Osswald
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1991
The catecholamines epinephrine and norepinephrine evoke specific beta-adrenergic responses in a variety of tissues.Examples of processes modulated by these agonists are chronotropic and inotropic cardiac responses, relaxation of smooth muscle, and lipolysis in adipose tissue.The facts that beta-adrenergic responses are limited to specific tissues and ...
Robert J. Lefkowitz, Jeffrey M. Stadel
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The catecholamines epinephrine and norepinephrine evoke specific beta-adrenergic responses in a variety of tissues.Examples of processes modulated by these agonists are chronotropic and inotropic cardiac responses, relaxation of smooth muscle, and lipolysis in adipose tissue.The facts that beta-adrenergic responses are limited to specific tissues and ...
Robert J. Lefkowitz, Jeffrey M. Stadel
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Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts.
New England Journal of Medicine, 1982M. Bristow +8 more
semanticscholar +1 more source
1981
The physiological effects of epinephrine and norepinephrine are caused by the interaction of these compounds with specific receptor molecules on the external surface of target cells. Since both epinephrine and norepinephrine are found in large quantities in the adrenal gland, these receptors are called adrenergic receptors.
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The physiological effects of epinephrine and norepinephrine are caused by the interaction of these compounds with specific receptor molecules on the external surface of target cells. Since both epinephrine and norepinephrine are found in large quantities in the adrenal gland, these receptors are called adrenergic receptors.
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Adrenergic receptors in the forehead microcirculation
Clinical Autonomic Research, 1996The presence of alpha- and beta-adrenoceptors in the forehead microcirculation was investigated in 49 healthy subjects. Local vascular responses to noradrenaline, isoprenaline and adrenergic antagonists, administered transcutaneously by iontophoresis, were monitored via laser Doppler flowmetry.
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