Results 71 to 80 of about 125,726 (303)
Advanced Science, EarlyView.A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang +10 more
wiley +1 more source
iScience, 2018 Summary: Adrenergic stimulation of brown adipose tissue (BAT) induces acute and long-term responses. The acute adrenergic response activates thermogenesis by uncoupling oxidative phosphorylation and enabling increased substrate oxidation.
Erin L. Brown +9 more
doaj +1 more source
Evolutionary loss of the ß1-adrenergic receptor in salmonids
, 2023 Supporting data for manuscript "Evolutionary loss of the ß1-adrenergic receptor in salmonids" published in General and Comparative Endocrinology.
William Joyce (12358495)
core +1 more source
NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity
Advanced Science, EarlyView.Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li +7 more
wiley +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Advanced Science, EarlyView.Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
Beta-adrenergic receptor regulation and airway inflammation
, 2005 There is ongoing concern that regular use of β2-agonists without additional use of inhaled steroids may contribute to an adverse outcome of asthma, which may in part be due to desensitization of the β2-adrenergic receptor (Chapter7 ). Therefore, there is
Oostendorp, Jaap, Oostendorp, Jaap,
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, 2008 There is at present an imperfect understanding of the effect of diet on availability of inhibitory receptors in fat cells during exercise among obese men. *Objective:* The purpose of this study was to determine whether diet results in
Roy R. Estrada +3 more
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Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective
Advanced Science, EarlyView.This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin +4 more
wiley +1 more source
PEG-coated gold nanoparticles attenuate β-adrenergic receptor-mediated cardiac hypertrophy
, 2017 Yuhui Qiao, Baoling Zhu, Aiju Tian, Zijian Li Department of Cardiology, Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Key Laboratory of ...
Zhu BL, Qiao YH, Tian AJ, Li ZJ
core
Melatonin Levels in 89 Individuals With Smith Magenis Syndrome
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley +1 more source