Results 91 to 100 of about 206,308 (257)

Which Patients With Dysfunctional Voiding Respond Well to Sacral Neuromodulation? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Dysfunctional voiding (DV) is characterised by fluctuating or intermittent urinary flow during voiding in neurologically normal individuals. Given the different definitions used and heterogeneous pathophysiologies, outcomes following sacral neuromodulation/sacral nerve stimulation (SNM/SNS) are variably reported.
Jalesh N. Panicker, Chris Harding, Hashim Hashim, Claire Hentzen, Nikita Bhatt, Arjun Nambiar, Brigitte Schurch, Mathijs de Rijk, Stefania Musco   +8 more
wiley   +1 more source

Phenotyping Overactive Bladder—Part 1: Are There Different Types of Urgency and Can They be Translated to Clinical, Urodynamic and Radiological Phenotyping? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Overactive bladder (OAB) is defined as urinary urgency, usually accompanied by increased daytime frequency and/or nocturia, with urgency urinary incontinence (OAB‐wet) or without (OAB‐dry), in the absence of urinary tract infection or other detectable disease.
John E. Speich, D. Carolina Ochoa, Pradeep Tyagi, Apostolos Apostolidis, Sanjay Sinha, Claire Hentzen, Marcus Drake, Paul Abrams, Alan J. Wein, Michel Wyndaele   +9 more
wiley   +1 more source

Trends and Racial/Ethnic Disparities in Pharmacologic and Surgical Management of Treated Female Patients With Urinary Incontinence

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background The current literature summarizes the trends in the surgical management of stress urinary incontinence (SUI) and not the general trends of management for all UI types in the US. Additionally, recent evidence on racial and ethnic disparities in UI related surgical utilization is limited. Objective To describe the currently prescribed
Rawan O. Almadfaa, Patricia R. Wigle, Alex C. Lin, Angelica Hardee, Jeff J. Guo, Ana L. Hincapie   +5 more
wiley   +1 more source

How Can We Personalize the Delivery of Onabotulinumtoxin‐A for Patients With Neurogenic Lower Urinary Tract Dysfunction?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang, William I. Jaffe, Ariana L. Smith   +2 more
wiley   +1 more source

Chinese Society of Pediatric Anesthesiology Guideline for Pediatric Sedation (2025)

Pediatric Anesthesia, EarlyView.
ABSTRACT Background With the increasing variety of pediatric diagnostic procedures, a growing number of children require sedation for diagnostic examinations. Appropriate sedation protocols guarantee the safety of children during sedation and improve its efficiency.
Xingrong Song, Dongxu Lei, Yu Cui, Zhen Du, Yingping Jia, Yue Jin, Hang Tian, Ying Xu, Lifang Yang, Jianmin Zhang, Jijian Zheng, Yunxia Zuo, Liang Zhong, John Zhong, Maryrose Osazuwa, Elizabeth Drum, Charles Dean Kurth, Yue Huang, Qinghua Huang, Heqi Liu, Wei Liu, Rui Ma, Dongpi Wang, Tingting Wang, Zixin Wang, Siwei Wei, Lei Yang, Rui Zhou, Liumei Chen, Weifeng Yu, Jun Li, Mazhong Zhang, Li Zhang, Shuangquan Qu, Shoudong Pan, Rong Wei, Liming Cheng, Yaolong Chen, Xueping Li, Zhenyu Tang   +39 more
wiley   +1 more source

Targeting fibrosis in the treatment of lower urinary tract dysfunction

The Journal of Pathology, EarlyView.
Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar, Sophia M Vrba, Emily A Ricke, Zsuzsanna Fabry, Matthew S Lee, Kevin T McVary, William A Ricke   +6 more
wiley   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Role of novel automated methods in pulse signal analysis to screen for sleep‐disordered breathing among patients on chronotropic medications

Sleep Research, EarlyView.
Abstract Study objectives To investigate the use of automated analysis to detect heart rate accelerations (HRAs) to screen for sleep‐disordered breathing (SDB) among patients who use chronotropic medications. Methods Nocturnal polysomnography (NPSG) recordings from 933 participants in the Sleep Heart Health Study were analyzed using an automated method
Nabila Ahmed, Moustafa Habra, Raya Nashef, Scott Maresh, Abed Najjar, Shivapriya Chandu, Adhithi Athikumar, Omar Ismail, Laurel A. Ravelo, Paul E. Peppard, M. Safwan Badr, Abdulghani Sankari   +11 more
wiley   +1 more source

In vitro and in vivo metabolism profiles of cathinone and pseudoephedrine: Discrimination between khat and pseudoephedrine uses

Journal of Forensic Sciences, EarlyView.
Abstract In the present study, the metabolism of khat (Catha edulis) and pseudoephedrine was compared with the aim of identifying objective criteria that could be used to discriminate between them for forensic and doping‐control purposes. An in vitro study using human liver microsomes and an in vivo study using rat urine were performed under harmonized
Jong Suk Park, Jun Sang Yu, Yejin Kim, Hee Seung Kim, Jae Chul Cheong, Jin Young Kim, Hye Hyun Yoo   +6 more
wiley   +1 more source