Results 101 to 110 of about 125,726 (303)

β-Adrenergic Receptor Kinase-1 Levels in Catecholamine-Induced Myocardial Hypertrophy

, 1999
Pressure overload ventricular hypertrophy is accompanied by dysfunctional β-adrenergic receptor signaling due to increased levels of the β-adrenergic receptor kinase-1, which phosphorylates and desensitizes β-adrenergic receptors.
Dolber, PC, Lefkowitz, RJ, Iaccarino, G, Koch, WJ   +3 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

β2-Adrenergic Receptor Activation Suppresses the Rat Phenethylamine Hallucinogen-Induced Head Twitch Response: Hallucinogen-Induced Excitatory Post-synaptic Potentials as a Potential Substrate

Frontiers in Pharmacology, 2018
5-Hydroxytryptamine2A (5-HT2A) receptors are enriched in layers I and Va of the rat prefrontal cortex and neocortex and their activation increases the frequency of glutamatergic excitatory post-synaptic potentials/currents (EPSP/Cs) onto layer V ...
Gerard J. Marek, Gerard J. Marek, Brian P. Ramos   +2 more
doaj   +1 more source

Alpha1a-Adrenergic Receptor Modulation Of Epileptiform Activity And Seizures

, 2019
The research herein aimed to increase our understanding about potential roles of adrenergic receptor subtypes in epileptic seizures and seizure-like (epileptiform) phenomena. Previous observations in our laboratory led us to hypothesize that the alpha1A-
Biggane, Joseph Patrick
core   +1 more source

The β₃-adrenergic receptor is dispensable for browning of adipose tissues

, 2017
Brown and brite/beige adipocytes are attractive therapeutic targets to treat metabolic diseases. To maximally utilize their functional potential, further understanding is required about their identities and their functional differences.
Jan Nedergaard, René T. F. Wouters, Jasper M. A. de Jong, Nathalie Boulet, Natasa Petrovic, Barbara Cannon   +5 more
core   +1 more source

Programming the Optoelectronic Properties of Atomically Precise Gold Nanoclusters Using the Conformational Landscape of Intrinsically Disordered Proteins

Chemistry – A European Journal, EarlyView.
ABSTRACT The rational design of hybrid nanomaterials with precisely controlled properties remains a central challenge in materials science. While atomically precise gold nanoclusters (Au‐NCs) offer molecule‐like control over a metallic core, tuning their optoelectronic behavior via surface engineering is often empirically driven.
Santiago Rodriguez, Sylvain Kumanski, Zeineb Ayed, Aurélie Fournet, Charlène Bouanchaud, Amin Sagar, Frédéric Allemand, Vladimir A. Baulin, Ute Resch‐Genger, Juan Cortés, Nathalie Sibille, Fabien Chirot, Karl David Wegner, Rodolphe Antoine, Xavier Le Guével, Pau Bernadó   +15 more
wiley   +1 more source

Adrenergic pathways in glycine-mediated feeding behavior: Evidence from layer chickens

Poultry Science
Glycinergic and adrenergic systems are integral to the regulation of meal consumption in avian species; however, the interactions between these systems have not been previously documented. This investigation was conducted to explore the interplay between
Hamed Zarei, Fatemeh Kashefi, Keyvan Hasani   +2 more
doaj   +1 more source

A single-nucleotide polymorphism of the beta 2-adrenergic receptor gene can predict pathological complete response to taxane- and platinum-based neoadjuvant chemotherapy in breast cancer

, 2018
Yueyao Du,* Tingting Yan,* Liheng Zhou, Wenjin Yin, Jinsong Lu Department of Breast Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China *These authors contributed equally to this work Background: Germline ...
Zhou L, Yin W, Lu J, Yan T, Du Y
core  

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). [PDF]

, 1987
The beta-adrenergic receptor kinase is an enzyme, possibly analogous to rhodopsin kinase, that multiply phosphorylates the beta-adrenergic receptor only when it is occupied by stimulatory agonists.
Codina, J, Lefkowitz, RJ, Weyand, I, Kühn, H, Caron, MG, Benovic, JL   +5 more
core  

The Effects of Adrenergic Receptor Agonist and Antagonists on Blood Fluidity in Rats

, 2010
The effects of stress on blood fluidity may be mediated through the sympathetic adrenergic nervous system. We investigated this proposition using a micro-channel array flow analyzer that mimics capillaries to study the effects of adrenergic receptor ...
AUNG, Steven K.H., SUNAGAWA, Masataka, ISHIKAWA, Shintaro, SATO, Takao, TOKITA, Erika, HISAMITSU, Tadashi, TANIGAWA, Hiroto, ISHINO, Tokuko   +7 more
core   +2 more sources